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Record W4406593601 · doi:10.1111/trf.18109

The <scp>REALITY</scp> of <scp>MINT</scp>: Caution before changing transfusion practice in myocardial infarction based on recent clinical trials

2025· article· en· W4406593601 on OpenAlexaff
Aryeh Shander, Mazyar Javidroozi, Kevin M. Trentino, Linda Shore Lesserson, Nelson Amaral, Caroline Evans, Irwin Gross, Jeannie Callum, Rawn Salenger, Daniel T. Engelman, Patrick Meybohm, Pierre Tibi

Bibliographic record

VenueTransfusion · 2025
Typearticle
Languageen
FieldMedicine
TopicAcute Myocardial Infarction Research
Canadian institutionsQueen's University
FundersGrifolsAtriCurePfizer
KeywordsMyocardial infarctionMedicineClinical trialIntensive care medicineInternal medicine

Abstract

fetched live from OpenAlex

AS has received consulting fees from CSL Vifor, Pharmacosmos, Accumen, I-Sep, Grifols, Lindis Corp, Octapharma, HbO2 Therapeutics LLC, and has served on the Data Safety Monitoring Board for RAPIDIRON trial. MJ declares no related conflicts of interest. KMT has received consulting fees from PBMe.Solutions, honoraria from Even Troop, and travel support for attending meeting from IFPBM. LSL has received consulting fee from CSL Behring and Vifor and has been board member in Society of Cardiovascular Anesthesiologists, National Board of Echocardiography and Society for Advancement of Patient Blood Management. NA has received honoraria for lectures and presentation as well as support for attending meetings and travel from Pharmacosmos. CRE has received honoraria from Pharmacosmos and Pfizer and travel support from Pharmacosmos and has served on the advisory boards for IV Iron in Cardiac Surgery and for Heart Failure for Pharmacosmos. IG has received consulting fees from Acumen, LLC, payment for participation in an advisory meeting from CSL Behring, and travel support from IFPBM and has served as a scientific associate for IFPBM. RS has received consulting fees from La Jolla, Terumo, and Encare, and honoraria from Atricure, Artivion, and Zimmer, and has served ERAS Cardiac Society. DTE has received consulting fees from Arthrex, Medela, Bioporto, and Atricure, has participated in the data safety monitoring board for Edwards Lifesciences and advisory boards for Renibus and Alexion, and has served as the president of ERAS Cardiac Society. PRT has served on Accumen Medical Advisory Board and has been a presenter for Hemosonics and CSL Vifor.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.043
metaresearch head score (Gemma)0.116
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.043
Threshold uncertainty score0.229

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0430.116
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0030.002
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0040.003
Open science0.0020.001
Research integrity0.0040.008
Insufficient payload (model declined to judge)0.0170.007

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.068
GPT teacher head0.420
Teacher spread0.352 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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