TransUAAE-CapGen: Caption Generation from Histopathological Patches through Transformer and UNet-Based Adversarial Autoencoder
Bibliographic record
Abstract
Captioning Whole Slide Images (WSIs) for pathological analysis is an essential but not extensively explored aspect of computer-aided pathological diagnosis. Challenges arise from insufficient datasets and the effectiveness of model training. Generating automatic caption reports for various gastric adenocarcinoma images is another challenge. In this paper, we introduce a hybrid method referred to as TransUAAE-CapGen to generate histopathological captions from WSI patches. The TransUAAE-CapGen architecture consists of a hybrid UNet-based Advereasrial Autoencoder (AAE) for feature extraction and a transformer for caption generation. The hybrid UNet-based AAE extracted complex tissue properties from histopathological patches, transforming them into low-dimensional embeddings. The embeddings are then fed into the transformer to generate concise captions. Our proposed method is validated using the PatchGastricADC22 dataset. The TransUAAE-CapGen model provides the best estimated accuracy of BLEU-4 = 86.8%, METEOR = 59.6%, a ROUGE = 89.3%, and CIDEr = 7.72%. Experimental analysis indicates that the TransUAAE-CapGen architecture outperforms the traditional LSTM-based model for the caption generation task. Our findings reveal that the proposed architecture can effectively generate accurate and precise reports for medical image analysis.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.003 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.002 |
| Insufficient payload (model declined to judge) | 0.004 | 0.002 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".