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Record W4406668594 · doi:10.14740/cr2009

Characterization of Intracardiac Flow in the Right Ventricle With Pressure and Volume Overload in Children

2025· article· en· W4406668594 on OpenAlexvenueno aff
Yasunobu Hayabuchi, Yukako Homma

Bibliographic record

VenueCardiology Research · 2025
Typearticle
Languageen
FieldMedicine
TopicPulmonary Hypertension Research and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineCardiologyVentricleInternal medicineIntracardiac injectionVolume overloadPressure overloadVentricular pressureVolume (thermodynamics)HemodynamicsHeart failure

Abstract

fetched live from OpenAlex

Background: Blood flow visualization using vector flow mapping (VFM) holds potential as a novel indicator of right ventricular (RV) function. Methods: This study included 12 patients with atrial septal defect (ASD group, mean (± standard deviation) age: 6.2 ± 1.5 years), six patients with pulmonary hypertension (PH group, mean age: 6.8 ± 2.3 years), and 35 healthy, age-matched children (control group, mean age: 7.3 ± 1.6 years). VFM data were obtained from the parasternal RV short-axis view. Results: VFM images in the majority of the control group showed a counterclockwise rotating vortex below the tricuspid anterior leaflet and clockwise vortex below the septal leaflet in early diastole. In late diastole, a clockwise vortex flow appeared at the RV apex to the outflow tract. In the ASD and PH groups, the formation of vortical flow below the tricuspid valve was decreased. Late-diastolic vortices also differed from the control group, with counterclockwise or no vortex flow seen in this phase in these groups. Flow energy loss (EL), kinetic energy (KE) and energetic performance index (EPI) were related to RV systolic and diastolic functions. Mean EL over one cardiac cycle (ELcycle) was significantly higher in the PH group than in the control group (P = 0.0471). KE of the RV inflow tract (KE-RVin) and outflow tract (KE-RVout) were significantly lower in the PH group than in the control and ASD groups (P < 0.05 each). Conclusions: These results suggest that RV vortex formation may be a factor in efficient ejection. EL, KE, and EPI may be applicable to evaluate RV contractility and diastolic function.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.174

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.309
Teacher spread0.296 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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