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Record W4406824097 · doi:10.1016/j.jeph.2024.202803

The association of medical cannabis use with quality of life in Illinois’ opioid alternative pilot program

2025· article· en· W4406824097 on OpenAlexaff
Cerina Dubois, Julie Bobitt, Lei Ding, Dean T. Eurich, Ashley A. Knapp, Neil Jordan

Bibliographic record

VenueJournal of Epidemiology and Population Health · 2025
Typearticle
Languageen
FieldMedicine
TopicCannabis and Cannabinoid Research
Canadian institutionsUniversity of Alberta
FundersNational Institute of Mental HealthUniversity of Illinois at Urbana-ChampaignIowa Department of Public Health
KeywordsCannabisMedical cannabisAssociation (psychology)OpioidPsychologyMedicinePsychiatryPsychotherapistInternal medicine

Abstract

fetched live from OpenAlex

BACKGROUND: In Illinois, the Opioid Alternative Pilot Program (OAPP) was launched to expand access to medical cannabis to use as a direct substitute for opioids. Although therapeutic benefits have been reported in reducing opioid use, there is an absence of literature that examines how medical cannabis use impacts an individual's quality of life (QoL). This study examines the association of medical cannabis use with QoL among the first enrollees in OAPP. METHODS: A survey was sent to enrollees between February and July 2019. Cannabis users (n=626) were compared to non-users (n=234) to determine whether there was an association between cannabis use within the past year and QoL. Ordered logistic regression and backwards stepwise regression modelling was used. RESULTS: Across the study sample of 860 participants, the average age was 47 years; 60 % of the cohort was male; 72 % were not of Hispanic, Latino, or Spanish origin; 67 % were married. Across the entire study sample, the average perceived QoL was 2.86 (between 'Good' and 'Fair'), with no statistically significant difference in QoL between the two groups (non-users: 2.85; cannabis users: 2.86; p=0.92). Logistic regression reported cannabis use within the past year did not have a statistically significant association with QoL (OR=1.33, 95% confidence interval, 0.85 to 2.08, p=0.21). DISCUSSION: Overall, there was no significant association between cannabis use within the past year and QoL. This may be attributed to pain being a qualifying condition to enter the program.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.016
metaresearch head score (Gemma)0.016
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.141
Threshold uncertainty score0.994

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0160.016
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.098
GPT teacher head0.469
Teacher spread0.371 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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