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Record W4406895577 · doi:10.1093/ehjdh/ztaf005

Artificial intelligence for the analysis of intracoronary optical coherence tomography images: a systematic review

2025· review· en· W4406895577 on OpenAlexaff
Ruben van der Waerden, Rick Volleberg, Thijs Luttikholt, Pierandrea Cancian, Joske van der Zande, Gregg W. Stone, Niels Ramsing Holm, Elvin Kedhi, Javier Escaned, Dario Pellegrini, Giulio Guagliumi, Shamir R. Mehta, Natalia Pinilla‐Echeverri, Raúl Moreno, Lorenz Räber, Tomasz Roleder, Bram van Ginneken, Clara I. Sánchez, Ivana Išgum, Niels van Royen, Jos Thannhauser

Bibliographic record

VenueEuropean Heart Journal - Digital Health · 2025
Typereview
Languageen
FieldMedicine
TopicCoronary Interventions and Diagnostics
Canadian institutionsMcMaster UniversityPopulation Health Research InstituteHamilton General HospitalMcGill UniversityHamilton Health SciencesRoyal Victoria Hospital
FundersMinisterie van Economische Zaken en KlimaatNederlandse Organisatie voor Wetenschappelijk Onderzoek
KeywordsOptical coherence tomographyComputer scienceArtificial intelligenceRevascularizationInterpretation (philosophy)Medical physicsRadiologyMedicineCardiology

Abstract

fetched live from OpenAlex

Intracoronary optical coherence tomography (OCT) is a valuable tool for, among others, periprocedural guidance of percutaneous coronary revascularization and the assessment of stent failure. However, manual OCT image interpretation is challenging and time-consuming, which limits widespread clinical adoption. Automated analysis of OCT frames using artificial intelligence (AI) offers a potential solution. For example, AI can be employed for automated OCT image interpretation, plaque quantification, and clinical event prediction. Many AI models for these purposes have been proposed in recent years. However, these models have not been systematically evaluated in terms of model characteristics, performances, and bias. We performed a systematic review of AI models developed for OCT analysis to evaluate the trends and performances, including a systematic evaluation of potential sources of bias in model development and evaluation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.008
metaresearch head score (Gemma)0.042
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.009
Threshold uncertainty score0.043

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0080.042
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0050.007
Bibliometrics0.0090.007
Science and technology studies0.0000.001
Scholarly communication0.0020.002
Open science0.0020.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.111
GPT teacher head0.427
Teacher spread0.316 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2025
Admission routes1
Has abstractyes

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