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Record W4406898396 · doi:10.1088/1361-6579/adaf73

PhysioEx: a new Python library for explainable sleep staging through deep learning

2025· article· en· W4406898396 on OpenAlexfundno aff
Guido Gagliardi, Antonio Luca Alfeo, Mario G. C. A. Cimino, Gaetano Valenza, Maarten De Vos

Bibliographic record

VenuePhysiological Measurement · 2025
Typearticle
Languageen
FieldMedicine
TopicObstructive Sleep Apnea Research
Canadian institutionsnot available
FundersNational Center for Advancing Translational SciencesNational Heart, Lung, and Blood InstituteUniversity of California, DavisDipartimenti di EccellenzaUniversità di PisaYork UniversityNational Institutes of HealthCase Western Reserve UniversityFonds Wetenschappelijk OnderzoekUniversity of WashingtonVlaamse regeringEuropean CommissionJohns Hopkins UniversityUniversity of Minnesota
KeywordsComputer scienceWorkflowToolboxPython (programming language)Artificial intelligencePreprocessorModular designDeep learningSleep medicinePipeline (software)Sleep (system call)Benchmark (surveying)Machine learningProgramming languageMedicine

Abstract

fetched live from OpenAlex

Abstract Objective. Sleep staging is a crucial task in clinical and research contexts for diagnosing and understanding sleep disorders. This work introduces PhysioEx (Physiological Signal Explainer), a Python library designed to support the analysis of sleep stages using deep learning (DL) and Explainable AI (XAI). Approach. PhysioEx provides an extensible and modular API for standardizing and automating the sleep staging pipeline, covering data preprocessing, model training, testing, fine-tuning, and explainability. It supports both low-resource devices and high-performance computing clusters and includes pretrained models based on the Sleep Heart Health Study dataset. These models support single-channel EEG and multichannel EEG-EOG-EMG configurations and are easily adaptable to custom datasets. PhysioEx also features a command-line interface toolbox allowing users to streamline the model development and deployment. The library offers a range of XAI post-hoc methods to explain model decisions and align them with expert knowledge. Main results. PhysioEx benchmark state-of-the-art sleep staging models in a standard pipeline. Enabling a fair comparison between them both on the training source and out-of-domain sources. Its XAI techniques provide insights into DL-based sleep staging by linking model decisions to human-understandable concepts, such as American Academy of Sleep Medicine-defined rules. Significance. PhysioEx addresses the need for a standardized and accessible platform for sleep staging analysis, combining DL and XAI. By supporting modular workflows and explainable insights, it bridges the gap between machine learning models and clinical expertise. PhysioEx is publicly available and installable via pip6 6 https://pypi.org/project/physioex/ . , making it a valuable tool for researchers and practitioners in sleep medicine.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Software · Consensus signal: none
Teacher disagreement score0.037
Threshold uncertainty score0.122

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0010.002
Open science0.0030.003
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0370.010

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.089
GPT teacher head0.332
Teacher spread0.243 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreSoftware

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes1
Has abstractyes

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