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Record W4406900976 · doi:10.3389/fpubh.2025.1557596

Editorial: Building public confidence in innovative mRNA vaccines

2025· editorial· en· W4406900976 on OpenAlexaff
Jia Hu, Kenneth Rabin, Cora Constantinescu, Heidi J. Larson, Scott C. Ratzan

Bibliographic record

VenueFrontiers in Public Health · 2025
Typeeditorial
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicRNA Interference and Gene Delivery
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsPublic healthMedicineComputational biologyBiologyNursing

Abstract

fetched live from OpenAlex

When we began work on this series some two years ago, we were acutely aware of a hardening 14 minority of global public opposition to vaccination. We did not, however, imagine that over the 15 intervening months, vaccination in general, and mRNA vaccines in particular, would escalate into a 16 political wedge issue that threatens to undermine the foundational role of immunization in public 17 health. 18Building public confidence in vaccines in general, and mRNA vaccines in particular, is more 19 important now than ever. The rapid development and launch of COVID-19 vaccines was estimated to 20 have saved over 14.4 million lives within the first year of their availability (

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.009
metaresearch head score (Gemma)0.028
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Editorial · Consensus signal: Editorial
Teacher disagreement score0.019
Threshold uncertainty score0.063

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0090.028
Meta-epidemiology (narrow)0.0040.001
Meta-epidemiology (broad)0.0030.002
Bibliometrics0.0030.001
Science and technology studies0.0040.003
Scholarly communication0.0070.006
Open science0.0040.002
Research integrity0.0190.025
Insufficient payload (model declined to judge)0.0190.017

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.303
Teacher spread0.288 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEditorial

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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