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Record W4406944220 · doi:10.1093/ofid/ofae631.2170

P-2013. Improving Access to <i>COVID-19</i> Treatment for Longterm Care (LTC) Residents: An Integrated Operational Approach

2025· article· en· W4406944220 on OpenAlexaboutno aff
Ajit Johal

Bibliographic record

VenueOpen Forum Infectious Diseases · 2025
Typearticle
Languageen
FieldHealth Professions
TopicGeriatric Care and Nursing Homes
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakPathogenic organismGerontologyVirologyInternal medicineOutbreakDisease

Abstract

fetched live from OpenAlex

Abstract Background Residents residing in Long-term care (LTC) facilities suffer disproportionately from severe outcomes of COVID-19. Antiviral treatment remains underutilized despite ongoing evidence in reducing severe disease in this high-risk group. In this quality improvement study conducted in British Columbia, Canada, barriers to treatment access were evaluated and addressed with educational resources to support the implementation of protocols within the LTC setting. Concern regarding COVID-19 outbreaks in Longterm Care Bar Chart categorizing pre- and post-responses from LTC staff regarding the concern of COVID-19 outbreaks at their facility during the study period. Methods Educational resources were developed by the study team and disseminated to Long-term care staff (n=564). Specifically, information for patients and their families about COVID-19 antiviral treatment, care plan templates for residents who opt in for treatment, and digital education videos for staff to support implementation of the aforementioned resources within the LTC setting. During the study period, January to April 2024, LTC staff were surveyed to determine the the usefulness of the resources. Comfort level managing drug-drug interactions Bar Chart categorizing pre- and post-responses reflecting LTC staff comfort levels in managing drug interaction with PAXLOVID therapy before and after the intervention. Results LTC staff respondents (n=78) consisted of Nurses (n=54), Pharmacists (n=13), and other staff (n=11) across LTC facilities (n=43) in Vancouver, BC. Most respondents (n= 31) expressed extreme concern for COVID-19 outbreaks in their facility, which remained unchanged during the study period (p=0.848). They reported unclear patient eligibility and drug-drug interactions as the biggest barriers to accessing COVID-19 treatment for their residents. After reviewing all educational materials with their respective facilities, respondents showed statistically significant changes in their comfort levels in discussing COVID-19 treatment with residents and their families (p< 0.01). However, no statistically significant change was seen in the pre-and post-evaluation in comfort levels managing drug interactions with COVID-19 antiviral therapy (p=0.155). Comfort level discussing PAXLOVID treatment Bar Chart categorizing pre- and post-responses reflecting LTC staff comfort levels in discussing PAXLOVID therapy with residents and their families Conclusion COVID-19 remains a concern in LTC settings, with staff encountering barriers to accessing antiviral treatment for their residents. An integrated operational approach, defined as curated resources highlighting information for residents and their families and care plan templates to support implementation, may help support timely access to antiviral treatments in this setting. Perceived Barriers to COVID-19 treatment in LTC Bar Chart categorizing pre- and post-responses reflecting LTC staff perceived barriers in accessing COVID-19 treatment, in the event of a confirmed positive test Disclosures Ajit Johal, BSP BCPP RPh, GSK: Grant/Research Support|GSK: Honoraria|Merck: Grant/Research Support|Merck: Honoraria|Moderna: Honoraria|Pfizer: Grant/Research Support|Pfizer: Honoraria|Sanofi Pasteur: Honoraria|Seqirus: Honoraria|Valneva: Honoraria

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.017
metaresearch head score (Gemma)0.018
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.224
Threshold uncertainty score0.445

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0170.018
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0020.001
Scholarly communication0.0030.001
Open science0.0020.005
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.054
GPT teacher head0.449
Teacher spread0.396 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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