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Record W4406962904 · doi:10.1161/str.56.suppl_1.tmp103

Abstract TMP103: Associations Between Trust in Health Information Sources and Perceptions on the Modifiability of Stroke and Dementia Risks Using a U.S. Based Cohort

2025· article· en· W4406962904 on OpenAlexaff
Sharon Ng, Jasper R. Senff, Reinier W. P. Tack, Benjamin Yong‐Qiang Tan, Koen B. Pouwels, Courtney Nunley, Aleksandra Pikula, Sarah Ibrahim, Amytis Towfighi, Cornelia M. van Duijn, Gregory L. Fricchione, Rudolph E. Tanzi, Nirupama Yechoor, Christopher D. Anderson, Jonathan Rosand, Sanjula Singh

Bibliographic record

VenueStroke · 2025
Typearticle
Languageen
FieldMedicine
TopicDiverse Approaches in Healthcare and Education Studies
Canadian institutionsUniversity Health Network
Fundersnot available
KeywordsMedicineDementiaCohortStroke (engine)PerceptionGerontologyDiseaseNeuroscienceInternal medicine

Abstract

fetched live from OpenAlex

Background: Trust in healthcare information sources, specifically in healthcare professionals (HCPs) influences people’s health-related knowledge and behaviors. Epidemiological studies demonstrate that approximately 45% of dementia and 60% of stroke risks are attributable to modifiable risk factors. However, limited data exist on associations between trust levels in HCPs and people’s perceptions on the modifiability of dementia and stroke risks from a United States cohort. Methods: We developed a survey based on validated questionnaires and distributed it to a cohort of all U.S. states via the online Prolific platform in 2023. First, we described cohort characteristics and levels of trust in health information sources and mediums. We performed multivariable regression analyses between high trust of all HCPs (i.e. primary care physicians, specialists, and nurses) with the perceptions that dementia and stroke risks are modifiable, adjusting for age, sex assigned at birth, race/ethnicity, level of education, and status of knowing someone with stroke/dementia. Lastly, we performed hierarchal cluster analyses to characterize clusters of trust patterns and assessed their differences. Results: Our cohort consisted of 1,478 participants (52% females, median age 46 years [IQR:32-60], and 75% non-Hispanic Whites) with levels of trusts shown in Figure 1 . Following multivariable regression analyses, participants who highly trusted all HCPs were statistically more likely to perceive that maintaining and changing health habits can reduce the risks of stroke or dementia (adjusted odds ratios presented in Figure 2 ). Lastly, three clusters of trust patterns emerged: (i) those who highly trust most sources (n=781), (ii) those who only trust official health sources (n=540) and (iii) those who have low trust of all sources (n=103) ( Figure 3 ). Participants who have low trust of all sources (Cluster iii) were less likely to have a post-secondary degree (57% vs 67-71%, p=0.04) and to perceive that stroke (80% vs 93-94%, p<0.01) and dementia (65% vs 76-81%, P<0.01) risks are modifiable, compared to the other clusters. Conclusion: Our study identified highly trusted sources of health information, characterized trust patterns in a large U.S. cohort, and assessed their association with perceiving stroke/dementia risks as modifiable. This novel data could assist us in developing targeted interventions for risk reduction using trusted sources and mediums.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.038
Threshold uncertainty score0.075

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.002
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.104
GPT teacher head0.379
Teacher spread0.275 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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