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Record W4407099573 · doi:10.1016/j.conctc.2025.101440

Bridging the gap: Understanding Latino willingness to participate in public health and clinical trials research across diverse subgroups

2025· article· en· W4407099573 on OpenAlex
Mary A. Garza, Yan Li, Craig S. Fryer, Luciana C. Assini‐Meytin, Segen Ghebrendrias, Christina Celis Puga, James Butler Lll, Sandra Crouse Quinn, Stephen B. Thomas

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueContemporary Clinical Trials Communications · 2025
Typearticle
Languageen
FieldMedicine
TopicEthics in Clinical Research
Canadian institutionsInstitute of Health Services and Policy Research
FundersNational Institute on Minority Health and Health DisparitiesOffice of the DirectorNational Institutes of HealthEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentUniversity of Pittsburgh
KeywordsBridging (networking)Public healthClinical trialFamily medicinePsychologyMedicineComputer sciencePathologyComputer security

Abstract

fetched live from OpenAlex

Background: Latino sub-groups remains limited. The purpose of this study was to investigate how knowledge, awareness and willingness to participate in research differs between US- born and immigrant Latinos. Methods: We conducted a population-based household telephone survey with Latino adults (N = 1264), with 68 % Mexican/Mexican American, 11 % Central/South American, 8 % Puerto Rican and the remaining 13 % self-identified as "Other". The "Building Trust Survey," included valid standardized instruments designed to assess knowledge of research, human subjects' protections, previous participation in research, immigrant status (nativity), length of time in the US, and country of origin. Results: The study found that Latinos who immigrated to the US as teens or young adults were more willing to participate in medical research than those born in the US. Willingness to "take" something in a study varied by Latino subgroup, immigration age, gender, and age. Analysis highlighted that Mexican/Mexican Americans (76 %) and Central/South Americans (74 %) indicated a willingness to participate in research but also were less likely to have been "Asked" to participate in research (9 % and 6 % respectively) compared to the other subgroups (p < .05). Conclusions: Insights from this study will inform the development of culturally tailored interventions aimed at successfully recruiting and retaining Latino populations in public health and clinical trials research, thereby contributing to more equitable and representative health outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.650
metaresearch head score (Gemma)0.761
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Science and technology studies, Research integrity
Consensus categoriesMetaresearch, Science and technology studies
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.766
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.6500.761
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0040.001
Bibliometrics0.0000.003
Science and technology studies0.0020.004
Scholarly communication0.0010.000
Open science0.0020.004
Research integrity0.0010.009
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.989
GPT teacher head0.789
Teacher spread0.199 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it