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Record W4407117809

Strychnine poisoning in nontarget species in western Canada: A retrospective case series (2014 to 2023).

2025· article· en· W4407117809 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
aboutThe title or abstract carries a Canadian signal from the geographic lexicon.

Bibliographic record

VenuePubMed · 2025
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicPlant-based Medicinal Research
Canadian institutionsUniversity of Saskatchewan
Fundersnot available
KeywordsStrychnineSeries (stratigraphy)MedicineBiologyPharmacologyPaleontology
DOInot available

Abstract

fetched live from OpenAlex

Background: Strychnine is a highly toxic, plant-derived alkaloid. It has historically been used in western Canada as a rodenticide for control of Richardson's ground squirrels; and in Alberta, as a predacide against wolves, coyotes, black bears, and skunks. However, nontarget species poisonings with strychnine have been widely documented in Canada and elsewhere. Poisonings manifest as acute neuroexcitation and are usually fatal. In March 2023, strychnine was banned in Canada for control of Richardson's ground squirrels, with concerns over wildlife poisonings cited. However, fatal poisonings have occurred in animals since the ban. Objective: To retrospectively characterize cases of nontarget species poisoning by strychnine in western Canada (British Columbia, Alberta, Saskatchewan, and Manitoba) based on diagnostic case records. Procedure: Diagnostic information from confirmed cases of strychnine poisoning from 2014 to 2023 was compiled from the records of Prairie Diagnostic Services (Saskatoon, Saskatchewan). Where available, epidemiologic data pertaining to year and month of submission, province, location of submitting veterinary clinic/enforcement office, species/breed, age, sample submitted, strychnine concentration, and case history were collected. Results: = 9). Poisoning in dogs occurred predominantly in medium and large breeds and in smaller population centers. Poisonings were diagnosed after the national ban was in effect. Conclusion and clinical relevance: This paper highlights the prevalence of nontarget species strychnine toxicosis in western Canada. Despite the recent national ban of strychnine, poisonings of nontarget species have continued.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.750
Threshold uncertainty score0.794

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.077
GPT teacher head0.390
Teacher spread0.313 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it