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Record W4407170397 · doi:10.3389/fonc.2025.1456563

Improving diagnostic precision in thyroid nodule segmentation from ultrasound images with a self-attention mechanism-based Swin U-Net model

2025· article· en· W4407170397 on OpenAlexaff
Changan Yang, Muhammad Awais Ashraf, Mudassar Riaz, Pascal Umwanzavugaye, Kavimbi Chipusu, Hongyuan Huang, Yueqin Xu

Bibliographic record

VenueFrontiers in Oncology · 2025
Typearticle
Languageen
FieldMedicine
TopicThyroid Cancer Diagnosis and Treatment
Canadian institutionsUniversity of Saskatchewan
Fundersnot available
KeywordsNodule (geology)SegmentationThyroid nodulesUltrasoundMechanism (biology)ThyroidMedicineComputer scienceArtificial intelligenceRadiologyComputer visionInternal medicineBiologyPhysics

Abstract

fetched live from OpenAlex

Background: Accurate segmentation of thyroid nodules in ultrasound imaging remains a significant challenge in medical diagnostics, primarily due to edge blurring and substantial variability in nodule size. These challenges directly affect the precision of thyroid disorder diagnoses, which are crucial for metabolic and hormonal regulation. Methods: This study proposes a novel segmentation approach utilizing a Swin U-Net architecture enhanced with a self-attention mechanism. The model integrates residual and multiscale convolutional structures in the encoder path, with long skip connections feeding into an attention module to improve edge preservation and feature extraction. The decoder path employs these refined features to achieve precise segmentation. Comparative evaluations were conducted against traditional models, including U-Net and DeepLabv3+. Results: The Swin U-Net model demonstrated superior performance, achieving an average Dice Similarity Coefficient (DSC) of 0.78, surpassing baseline models such as U-Net and DeepLabv3+. The incorporation of residual and multiscale convolutional structures, along with the use of long skip connections, effectively addressed issues of edge blurring and nodule size variability. These advancements resulted in significant improvements in segmentation accuracy, highlighting the model's potential for addressing the inherent challenges of thyroid ultrasound imaging. Conclusion: The enhanced Swin U-Net architecture exhibits notable improvements in the robustness and accuracy of thyroid nodule segmentation, offering considerable potential for clinical applications in thyroid disorder diagnosis. While the study acknowledges dataset size limitations, the findings demonstrate the effectiveness of the proposed approach. This method represents a significant step toward more reliable and precise diagnostics in thyroid disease management, with potential implications for enhanced patient outcomes in clinical practice.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.255
Threshold uncertainty score0.765

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.260
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations12
Published2025
Admission routes1
Has abstractyes

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Same venueFrontiers in OncologySame topicThyroid Cancer Diagnosis and TreatmentFrench-language works237,207