MétaCan
Menu
Back to cohort
Record W4407176582 · doi:10.33844/cjm.2025.6043

Primary Cutaneous Peripheral T-Cell Lymphoma-Not Otherwise Specified, Initially Misdiagnosed as Mycosis Fungoides: A Case Report and Literature Review

2025· article· en· W4407176582 on OpenAlex
Zara Saeed, Humaira Talat, Reema Mirza, Zuha Saleem

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueCanadian Journal of Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicCutaneous lymphoproliferative disorders research
Canadian institutionsnot available
Fundersnot available
KeywordsMycosis fungoidesPeripheral T-cell lymphomaMedicineLymphomaDermatologyPeripheralCutaneous T-cell lymphomaPathologyT cellImmunologyInternal medicineImmune system

Abstract

fetched live from OpenAlex

This report describes the case of a 52-year-old male who presented with a four-month history of multiple hyperpigmented lesions, predominantly affecting the trunk and upper limbs. On physical examination, numerous hyperpigmented patches and plaques were observed, with the largest lesion located on the right flank. Systemic examination revealed hepatomegaly, splenomegaly (tip of the spleen palpable), and right inguinal lymphadenopathy. The patient had no history of fever, weight loss, or other chronic illness. Initially, he was labelled as a case of mycosis fungoides; however, a repeat cutaneous biopsy, along with a lymph node biopsy, established the diagnosis of Primary Cutaneous Peripheral T-Cell Lymphoma – Not Otherwise Specified (pcPTCL-NOS). The patient was treated with six cycles of the CHOP regimen, resulting in initial resolution of the lesions. A post-chemotherapy PET scan showed no evidence of residual disease. This case emphasizes the importance of a comprehensive clinical evaluation, as the patient's acute history and systemic involvement hinted towards a far more aggressive disease process. Through a series of investigations, the correct diagnosis was made, facilitating the timely initiation of appropriate management.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.404
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.300
Teacher spread0.284 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it