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Record W4407192640 · doi:10.1136/rapm-2024-105609

Ten years of transitional pain service research and practice: where are we and where do we go from here?

2025· review· en· W4407192640 on OpenAlexafffund
Hance Clarke, Anna Waisman, Andrea Aternali, Kristina Axenova, Amjaad Almohawis, Kathryn Curtis, Joseph Fiorellino, Michelle Flynn, Praveen Ganty, Alexander Huang, Ziyang Hong, Rita Katznelson, Yuvaraj Kotteeswaran, Salima Ladak, Karim S. Ladha, Anna M. Lomanowska, Heather Lumsden-Ruegg, Molly McCarthy, Sarah Miles, Judith Nicholls, M. Gabrielle Pagé, Miki Peer, Brittany N. Rosenbloom, Daniel Santa Mina, Rachel Siegal, P. Maxwell Slepian, Ainsley M. Sutherland, Diana Tamir, Leeping Tao, Paul S. Tumber, Jeffrey S. Wieskopf, Callon M. Williams, Joel Katz

Bibliographic record

VenueRegional Anesthesia & Pain Medicine · 2025
Typereview
Languageen
FieldMedicine
TopicAnesthesia and Pain Management
Canadian institutionsWomen's College HospitalUniversité de MontréalCentre Hospitalier de l’Université de MontréalProvidence Health CareToronto Western HospitalUniversity of British ColumbiaYork UniversityNOSM UniversityUniversity Health NetworkToronto General HospitalUniversity of Toronto
FundersCanadian Institutes of Health ResearchCanadian Anesthesiologists' SocietyUniversity of TorontoWomen's College HospitalYork University
KeywordsRandomized controlled trialMedicineChronic painPerioperativeOpioidIntensive care medicineHealth carePhysical therapySurgeryInternal medicine

Abstract

fetched live from OpenAlex

Chronic postsurgical pain (CPSP) is a prevalent yet unintended consequence of surgery with substantial burdens to the individual and their family, the healthcare system, and society at large. The present article briefly reviews the evidence for transitional pain services (TPSs) that have arisen in an effort to prevent and mange CPSP and persistent opioid use, and provides an update on recent novel risk factors for CPSP. Available evidence from one randomized controlled trial (RCT) and three non-randomized cohort studies suggests that TPS treatment is associated with better opioid use outcomes, including fewer opioid tablets prescribed at discharge, better opioid weaning results, a lower incidence of new-onset chronic opioid use, and lower consumption of opioids even at later time points up to 1 year after surgery. Another RCT indicates TPS treatment can be enhanced by provision of perioperative clinical hypnosis. While these preliminary studies are generally positive, large-scale, RCTs are needed to provide a more definitive picture of whether TPSs are effective in reducing opioid consumption and improving pain and mental health outcomes in the short and long term. With the expansion of TPSs across North America and globally, perioperative care focused on reducing the transition to pain chronicity has the potential to help millions of patients. With additional evidence from well-controlled RCTs, TPSs are well poised to continue to evolve and strengthen the role of multidisciplinary care teams in the immediate postdischarge period and beyond.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.080
metaresearch head score (Gemma)0.149
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.080
Threshold uncertainty score0.425

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0800.149
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0040.003
Bibliometrics0.0040.006
Science and technology studies0.0060.014
Scholarly communication0.0190.033
Open science0.0040.011
Research integrity0.0130.023
Insufficient payload (model declined to judge)0.0070.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.085
GPT teacher head0.371
Teacher spread0.286 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2025
Admission routes2
Has abstractyes

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