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Record W4407209662 · doi:10.1162/imag_a_00486

Individual connectivity-based parcellations reflect functional properties of human auditory cortex

2025· article· en· W4407209662 on OpenAlexfundno aff
Maria Hakonen, Louisa Dahmani, Kaisu Lankinen, Jianxun Ren, Julianna Barbaro, Anna I. Blazejewska, Parker Kotlarz, Meiling Li, Jon̈athan R. Polimeni, Tori Turpin, Işıl Uluç, Danhong Wang, Hesheng Liu, Jyrki Ahveninen

Bibliographic record

VenueImaging Neuroscience · 2025
Typearticle
Languageen
FieldNeuroscience
TopicNeural dynamics and brain function
Canadian institutionsnot available
FundersNational Institute of Biomedical Imaging and BioengineeringNational Institutes of HealthNational Institute on Deafness and Other Communication DisordersCanadian Institutes of Health ResearchChina Postdoctoral Science Foundation
KeywordsAuditory cortexFunctional connectivityNeuroscienceComputer scienceCortex (anatomy)Human brainPsychology

Abstract

fetched live from OpenAlex

Neuroimaging studies of the functional organization of human auditory cortex have focused on group-level analyses to identify tendencies that represent the typical brain. Here, we mapped auditory areas of the human superior temporal cortex (STC) in 30 participants (15 women) by combining functional network analysis and 1-mm isotropic resolution 7T functional magnetic resonance imaging (fMRI). Two resting-state fMRI sessions, and one or two auditory and audiovisual speech localizer sessions, were collected on 3-4 separate days. We generated a set of functional network-based parcellations from these data. Solutions with 4, 6, and 11 networks were selected for closer examination based on local maxima of the Dice coefficients and Silhouette values. The resulting parcellation of auditory cortices showed intraindividual reproducibility of 69-78% between resting-state sessions and 62-73% between resting-state and task sessions, indicating moderate reproducibility. The interindividual variability was significantly larger than intraindividual variability (Dice coefficient: 57%-68%, p < 0.001), indicating that the parcellations also captured meaningful interindividual variability. The individual-specific parcellations yielded the highest alignment with task response topographies, suggesting that individual variability in parcellations reflects individual variability in auditory function. Connectional homogeneity within networks was also highest for the individual-specific parcellations. Furthermore, the similarity in the functional parcellations was not explainable by the similarity of macroanatomical properties of the auditory cortex. Together, our results show that auditory areas in STC can be segmented into functional subareas based on functional connectivity. Our findings also suggest that individual-level parcellations capture meaningful idiosyncrasies in auditory cortex organization.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.178
Threshold uncertainty score0.562

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.062
GPT teacher head0.294
Teacher spread0.233 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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