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Record W4407215823 · doi:10.1183/23120541.01370-2024

Top 10 priorities for chronic cough: Canadian James Lind Alliance Priority-Setting Partnership (CAN-COUGH)

2025· article· en· W4407215823 on OpenAlexafffundabout
Saif Samari, Ana Oliveira, Danica Brister, Elena Kum, Shawn D. Aaron, Darryl J. Adamko, Anurag Bhalla, Chris Carlsten, Maxime Cormier, Anne K. Ellis, Stephen K. Field, Krystelle Godbout, Paul Hernandez, Jeremy A. Hirota, Alan Kaplan, Renata Mancopes, Maria Sedeno, Maeve P. Smith, Robert A. Newman, Philip King, Tara. Gallagher, Sarah Butson, Dina Brooks, Imran Satia

Bibliographic record

VenueERJ Open Research · 2025
Typearticle
Languageen
FieldMedicine
TopicRespiratory and Cough-Related Research
Canadian institutionsUniversity of AlbertaQuebec Labrador FoundationToronto Rehabilitation InstituteMcGill University Health CentreUniversity of OttawaCanadian Lung AssociationDalhousie UniversityOttawa HospitalUniversity of British ColumbiaSt. Joseph’s Healthcare HamiltonUniversité LavalUniversity of SaskatchewanUniversity of CalgaryQueen's UniversityMcMaster University
FundersCanadian Institutes of Health Research
KeywordsMedicineChronic coughGeneral partnershipAllianceInternal medicineAsthmaLaw

Abstract

fetched live from OpenAlex

Background: Chronic cough significantly impacts individuals' quality of life and poses challenges for healthcare providers due to limited licensed treatments, side effects of available medications and difficulty accessing nonpharmacological interventions. Understanding priorities for research, education and knowledge dissemination from the perspectives of individuals with chronic cough and healthcare providers can guide future efforts. This study aimed to identify these key priorities in Canada. Study design and methods: We conducted a cross-sectional study using the James Lind Alliance (JLA) method to set priorities. Chronic cough was identified as the healthcare problem. Participants rated items related to research, education and knowledge dissemination in an online survey using a seven-point Likert scale. Results of the survey were reviewed by the Canadian Thoracic Society's (CTS) multidisciplinary working group and patient partners who engaged in a face-to-face Priority-Setting Partnership, to establish a "Top 10" priorities list for chronic cough. Results: 74 individuals with chronic cough and 62 healthcare providers completed the scoping survey. The top-rated priorities included enhancing knowledge of existing treatments, developing new treatments and improving diagnostic testing. The final "Top 10" priorities list emphasised the need for developing infrastructure for evaluating new treatments, improving understanding of biological mechanisms and raising awareness among the public and policymakers. Conclusion: This is the first priority-setting project for chronic cough, highlighting key areas to address in research, education and dissemination. The identified priorities will serve as a foundation for future efforts to improve the management and care of individuals with chronic cough.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.019
metaresearch head score (Gemma)0.024
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.096
Threshold uncertainty score0.696

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0190.024
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.003
Science and technology studies0.0200.003
Scholarly communication0.0070.003
Open science0.0030.012
Research integrity0.0020.004
Insufficient payload (model declined to judge)0.0070.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.149
GPT teacher head0.473
Teacher spread0.324 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes3
Has abstractyes

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