MétaCan
Menu
← Back to cohort
Record W4407226354 · doi:10.1183/13993003.02260-2024

Drug-induced lung disease: unwanted collateral damage

2025· letter· en· W4407226354 on OpenAlexaff
Yet H. Khor, Martin Kolb

Bibliographic record

VenueEuropean Respiratory Journal · 2025
Typeletter
Languageen
FieldMedicine
TopicInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Canadian institutionsMcMaster University
FundersNational Health and Medical Research Council
KeywordsMedicineCollateral damageDrugCollateralLungDiseaseInternal medicineCardiologyPharmacology

Abstract

fetched live from OpenAlex

Extract The term “drug”, originated from the French word “drogue”, refers to any substance or product that is used or intended to be used to modify or explore physiological systems or pathological states for the benefit of the recipient [1]. Since the start of the contemporary medicine era in the 19th century, there has been acceleration in drug discovery with over 800 new agents being approved by the US Food and Drug Administration over the past two decades [2, 3]. While drugs are fundamental for advancing health outcomes, they each are a double-edged sword that carries risks of unwanted side-effects. Of these, pulmonary toxicity in the form of drug-induced lung disease is among the most important, with potential detrimental impacts on health and even fatal sequelae.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.015
Threshold uncertainty score0.031

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.007
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0010.002
Scholarly communication0.0020.002
Open science0.0010.001
Research integrity0.0150.009
Insufficient payload (model declined to judge)0.0090.008

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.272
Teacher spread0.255 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueEuropean Respiratory Journal→Same topicInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis→French-language works237,207→