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Record W4407239334 · doi:10.2460/ajvr.24.09.0282

Machine learning predicts selected cat diseases using insurance data amid challenges in interpretability

2025· article· en· W4407239334 on OpenAlexaff
Barr N. Hadar, Zvonimir Poljak, Brenda N. Bonnett, Jason B. Coe, Elizabeth A. Stone, Theresa M. Bernardo

Bibliographic record

VenueAmerican Journal of Veterinary Research · 2025
Typearticle
Languageen
FieldMedicine
TopicVeterinary Oncology Research
Canadian institutionsUniversity of Guelph
Fundersnot available
KeywordsCATSRandom forestMedicineLogistic regressionPredictive modellingBreedInterpretabilityMachine learningStatisticsArtificial intelligenceComputer scienceInternal medicineMathematicsBiology

Abstract

fetched live from OpenAlex

Objective: To develop models for prediction of the onset of specific diseases in cats using pet insurance data and to evaluate their predictive performance. Methods: Agria Pet Insurance data from almost 550,000 cats (2011 to 2016) were analyzed and used to train predictive models for periodontal disease and skin tumors using breed, sex, and insurance claim history. Random downsampling and 1:1 matching by age, insurance duration, and time at risk balanced the dataset. Variables were then further processed, with random forest and conditional logistic regression used for analysis. Model accuracy was assessed through leave-one-out cross-validation, while variable importance plots, partial dependence plots, and coefficients were used for model interpretation. Results: Model accuracy ranged from 81.9% to 88.2% (P < .01, baseline 50%). Key predictors included prior insurance claims for "digestive," "whole body symptom," "skin," and "injury conditions," which may be nonspecific and predictive of various diseases. Maine Coon, Siamese, and Burmese cats were associated with periodontal disease-positive predictions, while domestic cats were linked with negative predictions. For skin tumors, Norwegian Forest Cats, Devon Rex and Sphynx cats, and Maine Coon cats were associated with positive predictions, whereas Birman and domestic cats were linked with negative predictions. Conclusions: This study presents a method of machine learning predictive analysis on pet insurance data, although more comprehensive medical information and approaches accounting for data characteristics may be necessary to develop clearer predictors. Clinical Relevance: To prevent or detect these conditions early, veterinarians can use the breed risk results to guide clients, especially those with high-risk breeds, by offering early advice on lifestyle and monitoring.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.011
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score0.023

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.011
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.271
GPT teacher head0.493
Teacher spread0.223 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations4
Published2025
Admission routes1
Has abstractyes

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