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Record W4407372305 · doi:10.1093/gerona/glaf026

Symposia Report of The Annual Biological Sciences Section Meeting of the Gerontological Society of America 2023, Tampa, Florida

2025· article· en· W4407372305 on OpenAlexaff
Blanka Rogina, Rozalyn M. Anderson, Nathan K. LeBrasseur, Sean Curan, Matthew J. Yousefzadeh, Bhaswati Ghosh, Gustavo Duque, Susan E. Howlett, Steven N. Austad, Ilja Demuth, Denis Gerstorf, Justin Korfhage, David B. Lombard, Peter Abadir, Kaare Christensen, James R. Carey, Susan C. Alberts, Fernando A. Campos, Juan Pablo Palavicini, Allyson K. Palmer, Justice Bell, Nathan Basisty, Rafael de Cabo, Ana P. Gomes, Vishwa Deep Dixit, Payel Sen, Joseph A. Baur, Shin‐ichiro Imai, Xiaoling Li, Gregorio Valdez, Miranda E. Orr, Scott D. Pletcher, Julie K. Andersen, Leanne Jones, David Castillo-Azofeida, Michael A. Bonaguidi, Yousin Suh, Francesca E. Duncan, Anna Murray, Weigler G Perry C, Kristopher Burkewitz, W. Mike Henne, Kai Zhou, Mustapha Bouhrara, Dan Benjamini, Shannon Kolind, Keenan A. Walker, David A. Reiter, Doug Dean, Vera Gorbunova, Vadim N. Gladyshev, Róbert Pálovics, Laura J. Niedernhofer, Rong Fan, Andreas Bueckle, Jennifer Hurley, Karyn A. Esser, Pankaj Kapahi, Shogo Sato, Nisi Jiang, Sarah Ashiqueali, Jose Diaz, Sidharth P. Mishra, Nuno Ralmundo, Reema Banarjee, Richard Allsopp, Lindsay M. Reynolds, Bohan Zhang, Paola Sebastiani, Stefano Monti, Nicholas J. Schork, Noa Rappaport

Bibliographic record

VenueThe Journals of Gerontology Series A · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetics, Aging, and Longevity in Model Organisms
Canadian institutionsDalhousie UniversityUniversity of British ColumbiaMcGill UniversityMcGill University Health Centre
FundersNational Institute of Diabetes and Digestive and Kidney DiseasesNational Institute of General Medical SciencesNational Institute on Aging
KeywordsGerontologyBiobankLongevityPsychological interventionHealthy agingBiologySenescenceEpigeneticsPhysiologyPsychologyMedicineBioinformaticsGeneticsPsychiatry

Abstract

fetched live from OpenAlex

The aging process is universal, and it is characterized by a progressive deterioration and decrease in physiological function leading to decline on the organismal level. Nevertheless, a number of genetic and nongenetic interventions have been described, which successfully extend healthspan and lifespan in different species. Furthermore, a number of clinical trials have been evaluating the feasibility of different interventions to promote human health. The goal of the annual Biological Sciences Section of the Gerontological Society of America meeting was to share current knowledge of different topics in aging research and provide a vision of the future of aging research. The meeting gathered international experts in diverse areas of aging research including basic biology, demography, and clinical and translational studies. Specific topics included metabolism, inflammaging, epigenetic clocks, frailty, senescence, neuroscience, stem cells, reproductive aging, inter-organelle crosstalk, comparative transcriptomics of longevity, circadian clock, metabolomics, and biodemography.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.159
Threshold uncertainty score0.531

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0020.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.000
Science and technology studies0.0010.000
Scholarly communication0.0020.001
Open science0.0010.002
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.1590.054

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.292
Teacher spread0.264 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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