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Record W4407416710 · doi:10.1002/mus.28351

Surgical Strategies for Functional Upper Extremity Reconstruction After Spinal Cord Injury

2025· review· en· W4407416710 on OpenAlexaff
Christopher S. Crowe, Yusha Liu, Catherine Curtin, Vincent R. Hentz, Scott H. Kozin, Ida K. Fox, Michael Berger

Bibliographic record

VenueMuscle & Nerve · 2025
Typereview
Languageen
FieldMedicine
TopicSpinal Cord Injury Research
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsMedicineSpinal cord injurySurgerySpinal cordPhysical medicine and rehabilitationAnatomy

Abstract

fetched live from OpenAlex

Spinal cord injuries (SCI) can substantially affect independence and quality of life, particularly by limiting upper extremity function. Surgical reconstruction offers the potential to restore motion in the hand, wrist, and elbow for those with deficits following cervical spinal cord injury. Techniques such as tendon transfer, tenodesis, and arthrodesis-often used in combination-are well-established strategies for enhancing upper extremity function. Nerve transfers have more recently been employed and differ from other procedures in that they are often time sensitive and should be performed before permanent muscle atrophy occurs. A comprehensive preoperative evaluation, including clinical examination and electrodiagnostic assessment, is essential to determine the availability and strength of donor tendons and nerves. The International Classification of Surgery for the Hand in Tetraplegia (ICSHT) system is the most utilized surgical classification for determining muscle that can be used for reconstruction. Based on this classification, prioritization is given to restoring elbow extension, wrist extension, pinch, and grasp. Postoperative rehabilitative therapy balances the need for immobilization while preventing joint stiffness and may also incorporate cortical retraining strategies to activate tendon and nerve transfers. Ultimately, a collaborative, interdisciplinary approach is essential for assessing the injury, determining operative candidacy, selecting the optimal treatment strategy, and providing tailored rehabilitation. This article explores the classification of SCI as it pertains to the upper limb, provides an overview of surgical options, describes the preoperative clinical and electrodiagnostic evaluation process, and discusses reconstructive strategies aimed at improving functional outcomes in individuals with SCI.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.974
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.107
GPT teacher head0.427
Teacher spread0.320 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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