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Record W4407463850 · doi:10.1016/j.ibmed.2025.100224

Hybrid deep learning and active contour approach for enhanced breast lesion segmentation and classification in mammograms

2025· article· en· W4407463850 on OpenAlexaff
Abdala Nour, Boubakeur Boufama

Bibliographic record

VenueIntelligence-Based Medicine · 2025
Typearticle
Languageen
FieldComputer Science
TopicAI in cancer detection
Canadian institutionsUniversity of Windsor
Fundersnot available
KeywordsArtificial intelligenceSegmentationActive contour modelDeep learningComputer sciencePattern recognition (psychology)LesionMammographyComputer visionMedicineImage segmentationBreast cancerPathologyInternal medicineCancer

Abstract

fetched live from OpenAlex

Accurate segmentation and classification of breast lesions in mammography images are crucial steps in effective breast cancer screening and diagnosis. This study presents a hybrid deep learning and active contour approach to automated mammogram analysis. The proposed methodology leverages the powerful feature extraction capabilities of deep convolutional neural networks and the precise boundary delineation of active contour models. A U-Net is trained on a large dataset of mammogram images to learn discriminative features and generate initial segmentation masks for breast lesions. Subsequently, an active contour refinement stage is employed to fine-tune the segmentation boundaries and enhance lesion delineation accuracy. This integration of active contour models (ACM) with deep learning techniques overcomes traditional image segmentation limitations. Morphological operations and energy minimization techniques are applied to the initial segmentation mask, resulting in highly accurate and refined lesion segmentation. This study investigates the synergistic integration of deep learning with Adaptive Contour Modeling for breast lesion segmentation. Our proposed U-Net_ACM model leverages the strengths of both approaches, demonstrating state-of-the-art performance and outperforming methods relying solely on deep learning or traditional image processing techniques. Evaluation on a test set reveals a 97.34 % accuracy, a Dice coefficient of 0.813, and an Intersection over Union of 0.891 for the U-Net_ACM model. These results surpass the performance of established pre-trained deep learning models such as VGG16, VGG19, and DeepLabV3, highlighting the benefits of the combined approach. This hybrid methodology offers a robust, automated solution for mammogram analysis, potentially improving breast cancer screening outcomes. The superior segmentation quality and overall performance demonstrated by the U-Net_ACM model suggest its potential for enhancing breast cancer screening and diagnosis in clinical settings.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.977
Threshold uncertainty score0.503

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.312
Teacher spread0.283 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations10
Published2025
Admission routes1
Has abstractyes

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