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Record W4407556581 · doi:10.26434/chemrxiv-2025-zhkrf

Democratizing self-driving labs through user-developed automation infrastructure

2025· preprint· en· W4407556581 on OpenAlexafffund
Brenden G. Pelkie, Sterling G. Baird, Eunice Aissi, Kenzo Aspuru-Takata, Yang Cao, Jin Hyun Chang, Kshitij Gambhir, Wm Salt Hale, Lucy Hao, Chance Hattrick, Jason E. Hein, Danli Luo, Owen A. Melville, Monique Ngan, Louie Lucas Bisgaard Nyeland, Nadya Peek, Maria Politi, Ethan Rajkumar, Alexander E. Siemenn, Blair Subbaraman, Sonya Vasquez, Jeffrey Watchorn, Wenyu Zhang, Rógvi Ziskason, Lilo D. Pozzo, Tonio Buonassisi, Tejs Vegge

Bibliographic record

VenueChemRxiv · 2025
Typepreprint
Languageen
FieldComputer Science
TopicIoT and Edge/Fog Computing
Canadian institutionsUniversity of British ColumbiaUniversity of Toronto
FundersNatural Sciences and Engineering Research Council of CanadaCanada Foundation for Innovation
KeywordsAutomationCritical infrastructureSelf drivingComputer securityInternet privacyComputer scienceWorld Wide WebBusinessEngineeringTransport engineering

Abstract

fetched live from OpenAlex

As self-driving labs become widely deployed in chemicals and materials research, interest in democratizing access to these platforms is growing. SDLs can be democratized by lowering their costs to increase accessibility and by creating systems that allow researchers to modify, extend, and share SDL tools to meet the needs of their science and contribute to the advancement of the SDL community. In particular, user-developed automation infrastructure is an important component of democratized SDL ecosystems. To advance community adoption of democratized SDL practices, we organized the “Democratizing Self-Driving Labs” workshop held at the 2024 Accelerate conference. As part of this workshop, the authors contributed to a demonstration of their user-developed automation infrastructure. 14 examples of custom built hardware, software, and workflows were shared. This workshop provided an opportunity for researchers to see user-developed infrastructure in action, learn about how they could integrate these projects into their work, and contribute to discussion about what is needed to advance the state of democratized SDLs. In this perspective, ten contributed examples of user-developed hardware and software from the workshop are highlighted. Despite a diverse array of projects, common motivations for pursuing user-developed infrastructure were cost savings and specification requirements that were unmet by commercially available products. Continuing to advance the state of user-developed automation infrastructure will require commitments to completing high-quality documentation for open-source hardware projects, pathways for materials researchers to learn hardware development skills, and more opportunities for researchers to share their infrastructure advancements, in addition to the scientific advancements that they enable.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.683
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0020.004
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.265
Teacher spread0.248 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2025
Admission routes2
Has abstractyes

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