A Bacillus subtilis xylanase improves nutrient digestibility, intestinal health and growth performance of broiler chickens undergoing an intestinal challenge
Bibliographic record
Abstract
The objective of this experiment was to evaluate the effects of a Bacillus subtilis xylanase on nutrient digestibility, intestinal health, and growth performance of broiler chickens undergoing an intestinal challenge. Nine hundred one-day-old Cobb 500 male chicks were randomly distributed into three dietary treatments with 10 replicates (30 birds/pen) until 42 d. Treatments were: Control (CT) diet, energy reduction (ER) diet, and the ER diet supplemented with B. subtilis endo 1,4-β-xylanase at 100 g/t (ER+xylanase). The ER diets had metabolizable energy reductions as per manufacturer guidelines: 80, 82, 87, and 92 kcal/kg for pre-starter, starter, grower, and finisher, respectively. All birds were challenged with Eimeria spp. on d 1 and Clostridium perfringens on d 12-14. Feed intake, body weight gain (BWG), and feed conversion ratio (FCR) were evaluated weekly. On d 17, the intestinal permeability was determined using fluorescein isothiocyanate-dextran (FITC-d) as marker. On d 21, I See Inside (ISI) methodology assessed intestinal alterations. On days 21 and 42, nutrient digestibility and cecal short-chain fatty acids (SCFA) concentrations were calculated. Data underwent ANOVA or Kruskal-Wallis tests, followed by Fisher or Dunn tests, respectively. From 0 to 42 d, broilers fed the ER+xylanase diet had greater (P = 0.046) BWG than birds fed the ER diet, while FCR showed improvements in CT and ER+xylanase diets. Broilers fed the ER+xylanase diet had improved intestinal integrity with the lowest (P = 0.017) serum FITC-d concentration and highest (P = 0.057) Mucin-2. Pancreas ISI scores were worsened (P = 0.034) in CT and ER diets compared to ER+xylanase diet. Ileal digestibility of DM and energy, and SCFA were greater (P ≤ 0.006) in broilers fed the ER+xylanase diet compared to ER diet. In conclusion, the B. subtilis xylanase supplementation improved nutrient digestibility, enhanced intestinal barrier integrity and increased SCFA concentrations which improved growth performance in broilers undergoing an intestinal challenge. Results indicated that this xylanase was able to compensate the energy reduction in corn-soy diets fed to broiler chickens.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".