X chromosomal monosomy with bilateral ovotestes in a Labrador Retriever dog
Bibliographic record
Abstract
A 2 year intact, phenotypically female Labrador Retriever dog was presented for evaluation of persistent white vaginal discharge after a perceived normal estrous cycle. On repeat evaluations, the dog was determined to be in persistent cytologic estrus ~ for 2 months. Abdominal ultrasonography revealed suspected bilateral ovarian cysts and cystic endometrial hyperplasia. After ultrasound-guided cystic aspiration, the dog was treated with a 3 day course of gonadotropin-releasing hormone (GnRH). Four months after initial treatment, the dog developed behavioral and physical signs of estrus that lasted ~ for 4 weeks; systemic progesterone concentrations never increased > 1.0 ng/ml. Repeat abdominal ultrasonography revealed another cyst-like structure on the right gonad. Similar treatment (cyst aspiration and GnRH treatment) was given. Paired cystic fluid and blood serum hormone concentrations were analyzed at each aspiration; testosterone concentrations were higher in serum and cystic fluid. Ovariohysterectomy and karyotyping diagnoses were bilateral ovotestis and X chromosomal monosomy (77, XO).
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".