Amended classification of renal tumours 2013 (International Society of Urological Pathology Vancouver Classification of Renal Neoplasia)
Bibliographic record
Abstract
vod: Ndory ledvin pedstavuj irok spektrum histopatologickch jednotek. Jejich aktuln klasifikace WHO se datuje do roku 2004, tedy je ji 10 let star. Nicmn v jnu 2013 byla vydna aktualizace vytvoen ISUP (International Society of Urological Pathology). V lnku pinme pehled podstatnch zmn pohledem klinika.Pehled podstatnch zmn: Bylo pidno pt novch epitelilnch tumor: tubulocystick renln karcinom RK, RK spojen se zskanou cystzou ledvin, svtlobunn (tubulo-) papilrn RK, MiT translokan RK (zejmna t(6;11) RK) a syndrom hereditrn leiomyomatzy a renlnho karcinomu. Ti dal renln karcinomy jsou pidny jako provizorn jednotky: thyroidlike follicular renal cell carcinoma (RCC); succinate dehydrogenase B deficiency-associated RCC; ALK translocation RCC.V rmci existujcch jednotek byly provedeny dl zmny: Multicystick svtlobunn RK (SRK) (dve multilokulrn cystick renln karcinom) byl logicky zaazen pod SRK jako jeho podjednotka s nzkm malignm potencilem. Onkocytick papilrn RK (PRK) nebyl zatm uznn jako dal podjednotka PRK. Hybridn onkocytick chromofobn tumor existujc ve tech klinicko-patologickch situacch (Birt-Hogg-Dub syndrom, renln onkocytza a sporadick) je azen jako podjednotka chromofobnho RK. Byly doplnny nov poznatky o RK ze sbrnch kanlk, medulrnm RK, mucinzn tubulrn a vetenobunn RK. K angiomyolipomu pidna cystick varianta AML a upraven byl pohled na epitelioidni variantu AML. Cystick nefrom a smen epiteliln a stromln tumor zaazeny do jedn spolen skupiny. Synoviln sarkom byl pesunut mezi sarkomy.Pracovn skupiny doporuuje tuto klasifikaci nazvat jako ISUP vancouversk klasifikace.Zvr: S ISUP vancouverskou klasifikac ndor ledvin by se mli urologov seznmit, nebo pin adu podstatnch zmn a lze pedpokldat, e bude zkladem nov WHO klasifikace.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.006 | 0.018 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.003 |
| Bibliometrics | 0.012 | 0.010 |
| Science and technology studies | 0.002 | 0.001 |
| Scholarly communication | 0.003 | 0.003 |
| Open science | 0.003 | 0.003 |
| Research integrity | 0.002 | 0.006 |
| Insufficient payload (model declined to judge) | 0.023 | 0.010 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".