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Record W4407946140 · doi:10.1162/jocn_a_02317

Individual Differences in Visual versus Semantic Neural Reactivation: Evidence from Severely Deficient Autobiographical Memory

2025· article· en· W4407946140 on OpenAlexafffund
Michael B. Bone, Brian Levine, Bradley R. Buchsbaum

Bibliographic record

VenueJournal of Cognitive Neuroscience · 2025
Typearticle
Languageen
FieldNeuroscience
TopicMemory and Neural Mechanisms
Canadian institutionsUniversity of TorontoBaycrest Hospital
FundersCanadian Institutes of Health Research
KeywordsPsychologyVisual memorySemantic memoryAutobiographical memoryRecallCognitive psychologyVisual cortexHippocampusEpisodic memoryExplicit memoryNeuroscienceCognition

Abstract

fetched live from OpenAlex

Visual memory is intrinsically linked to the reinstatement of low-level visual features, such as edges and luminosity, within early visual cortex. However, individuals with severely deficient autobiographical memory (SDAM) cannot vividly recollect autobiographical experiences yet display normal everyday functioning. We hypothesized that such individuals would depend on semantic features instead of low-level visual features during a challenging visual recognition task due to impaired communication of low-level visual information between the posterior hippocampus and early visual cortex. Two methods were used to measure the content of memory derived from fMRI data collected at encoding and retrieval: one directly measuring feature-specific neural reactivation within the hippocampus and other cortical regions, and another modeling top-down inference to assess the influence of semantic-based recall on reactivation within early visual cortex. In accord with prior findings, recognition accuracy in non-SDAM individuals was linked to low-level visual reactivation within early visual cortex and posterior hippocampus. As predicted, this association was diminished in SDAM individuals, whose recognition accuracy was instead linked to semantic-based reactivation. In addition, non-SDAM individuals exhibited communication of low-level visual information between early visual cortex and hippocampus, whereas SDAM individuals showed communication of semantic information. Given that SDAM participants' performance on the visual memory task was equivalent to non-SDAM subjects, our findings suggest that SDAM individuals successfully compensate for impaired low-level visual memory through semantic recall and highlight the essential role of feature-specific reactivation measures in identifying distinct neural pathways to memory performance.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.012
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.320
Threshold uncertainty score0.997

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.012
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0000.001
Scholarly communication0.0000.001
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.158
GPT teacher head0.365
Teacher spread0.208 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes2
Has abstractyes

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