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Record W4408000399 · doi:10.1177/15910199251323117

A visual journey through medium vessel occlusion strokes: From diagnosis to treatment

2025· review· en· W4408000399 on OpenAlexaff
Alexander Stebner, Salome Bosshart, Satoru Fujiwara, Roberto Souza, Mariana Bento, Johanna M. Ospel

Bibliographic record

VenueInterventional Neuroradiology · 2025
Typereview
Languageen
FieldMedicine
TopicAcute Ischemic Stroke Management
Canadian institutionsHotchkiss Brain InstituteFoothills Medical CentreUniversity of Calgary
Fundersnot available
KeywordsMedicineThrombolysisDigital subtraction angiographyOcclusionStroke (engine)RadiologyIschemiaCollateral circulationAcute strokeAngiographyCardiologyInternal medicineTissue plasminogen activator

Abstract

fetched live from OpenAlex

Acute ischemic stroke occurs when a blood clot obstructs cerebral blood flow, leading to ischemia and potentially irreversible brain damage. While large vessel occlusions are known for their catastrophic effects, medium vessel occlusions (MeVOs) also contribute significantly to stroke-related disability. These occlusions, which occur in smaller, mid-sized vessels, can result in substantial neurological deficits depending on their location and the availability of collateral circulation. The detection of MeVOs poses unique diagnostic challenges, as their subtle presentations are often overlooked in standard imaging. Timely and accurate identification is critical for initiating appropriate therapies, including intravenous thrombolysis, endovascular thrombectomy, and secondary prevention measures. This editorial takes you on a visual journey through the world of MeVOs, exploring their locations, challenging cases, and the diverse techniques used to identify them. With detailed illustrations, it demonstrates how to recognize these occlusions on both advanced and conventional imaging, including guidance on spotting them on digital subtraction angiography. Finally, it delves into how these strokes are treated, offering a comprehensive and engaging look at the unique challenges and solutions in MeVO management.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.681
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0030.002
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.065
GPT teacher head0.404
Teacher spread0.339 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes1
Has abstractyes

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