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Record W4408004415 · doi:10.3389/fitd.2025.1544842

Community-based models for neglected tropical diseases affecting the skin: a scoping review

2025· review· en· W4408004415 on OpenAlexaff
India Hotopf, Shahreen Chowdhury, Guillermo Robert, Mary Ellen Sellers, Maneesh Phillip, Anil Fastenau, Maria del Mar Marais, Constanze Vettel, Mijanur Rahman, Rajni Kant Singh, Becks Hill, Ahmed Bekere, Laura Dean

Bibliographic record

VenueFrontiers in Tropical Diseases · 2025
Typereview
Languageen
FieldMedicine
TopicParasitic Diseases Research and Treatment
Canadian institutionsCustom Security Industries (Canada)
Fundersnot available
KeywordsNeglected tropical diseasesTropical diseaseGeographyMedicinePathologyDisease

Abstract

fetched live from OpenAlex

Skin neglected tropical diseases (NTDs) cause physical impairments, and socioeconomic and mental health impacts, often exacerbated by social stigma. The WHO 2030 road map calls for integrated, person-centred care; community-based groups (CBGs) present a community-led solution. However, evidence is limited and CBGs are not consistently being operationalised across health systems. The UPLIFT study is developing and piloting a harmonised CBG tool. This scoping review aimed to identify preferred practices in existing skin-NTD CBG models and recommend a holistic framework for best practice. We searched four peer-reviewed databases and key organisations’ websites, for terms related to CBGs and skin-NTDs. Eligible studies explored community models and skin NTDs and were published in English from 2000 onwards. Studies with quantitative, qualitative, or mixed method approaches, and secondary analysis or evidence synthesis were eligible. Studies failing to fulfil the criteria, opinion pieces, cross-sectional surveys, editorials, and case studies were excluded. Outcomes on key CBG domains were thematically identified and explored from literature and discussions with subject matter experts: self-care, mental health, livelihood, and governance. Data were compiled in Excel and charted according to CBG domain and other key information (e.g., outcome and method of measurement), before writing up findings thematically. Fifty-four eligible citations were identified, including 38 peer-reviewed papers. Most studies were pretest/posttests conducted in Asia, targeting mainly leprosy, with heterogeneity in study designs and evaluative measures. Only four studies explored all CBG domains, with few CBGs including formal mental health support, livelihood activities and advocacy and awareness activities. Current research on the burden of skin-NTDs is predominantly focused on leprosy, leaving a significant gap in research on other skin-NTDs, particularly in the African region. Most CBGs are failing to integrate into health systems and mainstream important programmatic components such as sustainability and gender considerations. To address these gaps and work towards a harmonised CBG approach, we present a framework of best practice and recommend further research, targeting multiple skin-NTDs in unison.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.478
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.003
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0040.002
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.061
GPT teacher head0.411
Teacher spread0.350 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2025
Admission routes1
Has abstractyes

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