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Record W4408046882 · doi:10.1016/j.ijid.2024.107583

Evaluation of IFN-γ ELISA assays for quantifying interferon-gamma in Canadian bison

2025· article· en· W4408046882 on OpenAlexaboutno aff
Josephine Chileshe, Dr Todd Shury

Bibliographic record

VenueInternational Journal of Infectious Diseases · 2025
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicAnimal Disease Management and Epidemiology
Canadian institutionsnot available
Fundersnot available
KeywordsInterferon gammaVirologyInterferon γImmunologyInterferonBiologyCytokine

Abstract

fetched live from OpenAlex

was distributed to 385 clinical employees, including physicians, pharmacists, nurses, and lab specialists.Descriptive statistics and non-parametric tests (Mann-Whitney and Kruskal-Wallis) analyzed 5-point Likert scale (1 = Strongly Disagree, 2 = Partially Disagree, 3 = Neutral, 4 = Partially Agree, 5 = Strongly Agree) survey data, comparing median scores across ASP elements and employee groups, with significance at P < 0.05.Qualitative data from semi-structured interviews were thematically analyzed using NVIVO software.Results: Document reviews showed that ASPs at EHS hospitals are centrally managed, with all 12 hospitals meeting most core elements (Mode = 3).Variability in median scores highlighted challenges in formalizing programs across facilities.Survey results indicated partial dissemination of all core elements (median = 4).Leadership commitment (mean = 4.41, SD + 1.04) and pharmacy expertise (mean = 3.93, SD + 1.09) showed higher scores compared to other elements.Significant differences were observed between ASP members and non-members (p < 0.05), trained and untrained employees (p < 0.001), and across hospitals (p = 0.032).Qualitative analysis revealed strong strategic commitment and facility-driven ASP implementation supported by collaborative leadership, tailored education, and provider engagement.Key barriers included a lack of trust in ASP teams, physician resistance, absence of a competency framework, inadequate professional training, and limited access to rapid diagnostics.Discussion: Despite structural barriers and variability in adoption, EHS demonstrates strong leadership commitment, pharmacist engagement, and strategic implementation of ASP interventions.This first mixed-methods study in the UAE, utilizing data triangulation, benchmarks ASP practices against CDC standards.Findings align with practices in non-EHS government hospitals and high-income countries like Norway and Germany but contrast with some MENA region trends.Conclusion: EHS has established a robust foundation for sustainable ASPs, evidenced by adequate adoption and alignment with international frameworks.This study contributes to regional ASP benchmarking and highlights the need for further research to evaluate cost-effectiveness and clinical outcomes, including reductions in mortality and morbidity.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.351
Threshold uncertainty score0.706

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.004
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0030.002
Science and technology studies0.0020.001
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.063
GPT teacher head0.355
Teacher spread0.292 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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