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Record W4408049971 · doi:10.1016/j.onehlt.2025.101006

Integrated opisthorchiasis control through the EcoHealth/one health approach: 15 years of success and experiences with the Lawa model

2025· article· en· W4408049971 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

fundA Canadian funder is recorded on the work.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueOne Health · 2025
Typearticle
Languageen
FieldMedicine
TopicZoonotic diseases and public health
Canadian institutionsnot available
FundersGrand Challenges CanadaNational Research Council of ThailandInternational Development Research Centre
KeywordsOpisthorchiasisEnvironmental healthMedicinePathology

Abstract

fetched live from OpenAlex

Opisthorchis viverrini infection remains a major health problem in Northeast Thailand and the Mekong region impacting over 12 million and causing bile duct cancer. Using an EcoHealth/One Health approach at Lawa Lake in Thailand, our integrated control program achieved a substantial reduction in liver fluke prevalence from 60 % to <5 % over 15 years. Key interventions included chemotherapy, collaboratively designed health education, ecosystem modification, and community participation. Infections in intermediate hosts, Bithynia snails and Cyprinoid fish, are now undetectable. Improved community knowledge resulted in healthier practices. The “Lawa Model”, a recognized model for liver fluke control, is now a training hub being scaled up in Thailand and the Mekong region. This program demonstrates how One Health strategies can address complex health and ecological challenges and aligns with WHO recommendations. The success of the Lawa Model demonstrates the efficacy of integrated One Health interventions against endemic parasitic diseases.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.553
Threshold uncertainty score0.992

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.038
GPT teacher head0.327
Teacher spread0.289 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it