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Record W4408124030 · doi:10.1177/09564624251324978

HIV self-testing relative to the landscape of HIV testing in Ontario, Canada

2025· article· en· W4408124030 on OpenAlexafffundabout
Patrick O’Byrne, Maya Kesler, Lauren Orser, Michael Kwag, Brook Biggin, Christopher J. Draenos

Bibliographic record

VenueInternational Journal of STD & AIDS · 2025
Typearticle
Languageen
FieldMedicine
TopicHIV/AIDS Research and Interventions
Canadian institutionsUniversity of TorontoCommunity Based Research CentreOntario HIV Treatment NetworkUniversity of Ottawa
FundersOntario HIV Treatment NetworkPublic Health Agency of Canada
KeywordsMedicinePublic healthDemographyHuman immunodeficiency virus (HIV)Test (biology)Environmental healthFamily medicineGerontologyPathology

Abstract

fetched live from OpenAlex

BackgroundHIV self-testing may help achieve the UNAIDS 95-95-95 targets because it has the potential to increase testing among equity-denied communities. In 2023, the Public Health Agency of Canada made a one-time $8 million investment into HIV self-testing. We sought to evaluate the outcomes of HIV self-testing, compared to serology in Ontario, Canada.MethodsWe submitted data requests to all agencies involved HIV self-test distribution in Ontario, Canada for 2022-2023. We obtained matching data from the Public Health Ontario Laboratory. We then analyzed for unique test, unique tester, and positivity rate per testing modality.ResultsDuring the analysis period, we found that the laboratory completed an average of 53,606 tests per month for an average number of 44,671 unique persons. For self-tests, there was an average of 1700 tests distributed per month to an average of 678 unique persons. The positivity rate for self-testing was 0.27%, compared to 0.1% for serology.ConclusionsOur results highlight that self-testing can play a role but will not, alone, achieve the UNAIDS 95-95-95 targets. In our jurisdiction, self-testing corresponded with a higher positivity rate but accounted for only a minority of new diagnoses. In short, HIV self-testing is a tool, but not the solution to the HIV epidemic.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.206
Threshold uncertainty score0.702

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.313
Teacher spread0.289 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes3
Has abstractyes

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