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Record W4408191410 · doi:10.26434/chemrxiv-2025-6v1sf

Machine learning for the experimental and computational development of heterogeneous catalysis

2025· preprint· en· W4408191410 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueChemRxiv · 2025
Typepreprint
Languageen
FieldMaterials Science
TopicMachine Learning in Materials Science
Canadian institutionsCanadian Institute for Advanced ResearchVector InstituteUniversity of Toronto
Fundersnot available
KeywordsDevelopment (topology)Computer scienceArtificial intelligenceMathematics

Abstract

fetched live from OpenAlex

Machine learning techniques have emerged as a useful tool for identifying complex patterns and correlations in large datasets. These techniques could be particularly useful in heterogeneous catalysis research for enabling the correlation of the catalyst performance to its physicochemical properties. So far in the chemistry and material science communities, machine learning models have mostly been built on high-throughput quantum chemistry calculations, and only selected case studies have led to the experimental discovery of improved catalyst materials. The slow pace and limited number of scientific breakthroughs may be attributed to simplistic assumptions about catalyst structure in quantum chemistry calculations and the incomplete experimental data available. Therefore, we believe that the development of high-throughput approaches closely coupled with machine-learning-based approaches could help accelerate experimental catalysis research. To aid the community, we bring together the available body of work applying high-throughput approaches and machine learning to the development of solid heterogeneous catalysis. We offer an objective view of the trends in the field by performing a detailed and systematic comparison of papers based on the (1) the ML method, the features used as model input and output, (3) the material, device or reaction investigated, (4) the dataset size, and (5) the overall achievement. Furthermore, for models reporting unitless R2 values, we quantitatively analyze the model performance as a function of the features used, the reaction type and the dataset size.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.260
Threshold uncertainty score0.688

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.295
Teacher spread0.273 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it