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Record W4408200364 · doi:10.31925/farmacia.2024.6.7

VITAMIN D IMPACT ON STRESS AND COGNITIVE DECLINE IN OLDER ROMANIAN ADULTS

2024· article· en· W4408200364 on OpenAlexaboutno aff
Justin Aurelian

Bibliographic record

VenueFARMACIA · 2024
Typearticle
Languageen
FieldMedicine
TopicVitamin D Research Studies
Canadian institutionsnot available
Fundersnot available
KeywordsRomanianCognitive declineCognitionStress (linguistics)GerontologyVitamin D and neurologyPsychologyMedicinePsychiatryInternal medicineDementiaDisease

Abstract

fetched live from OpenAlex

Vitamin D plays a key role in ageing-related cellular processes, such as inflammation, oxidative stress and mitochondrial dysfunction.Vitamin D deficiency is prevalent among older adults and has been linked to cognitive decline, mood disorders and various age-related diseases.This study evaluated the correlation between serum vitamin D levels and stress resilience, cognitive decline and successful ageing in older Romanian adults.A cross-sectional clinical trial was conducted with 89 participants over 55.Serum vitamin D levels were measured using chemiluminescence analysis.At the same time, the cognitive function was assessed through the Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MOCA) and the Geriatric Depression Scale.Stress and resilience were evaluated using the Perceived Stress Scale and Siebert Resilience Test.Low vitamin D levels have been associated with cognitive impairment, as measured by the MMSE and MOCA.However, no significant relationship was found between vitamin D levels and stress or resilience scores.This study indicates that vitamin D may play a significant role in preventing cognitive decline among older adults; however, its effects on stress and resilience necessitate further investigation. RezumatVitamina D joacă un rol important în procesele celulare asociate cu îmbătrânirea, cum ar fi inflamația, stresul oxidativ și disfuncția mitocondrială.Carența de vitamină D este răspândită în rândul adulților în vârstă și a fost legată de deficitul cognitiv, tulburările de dispoziție și alte boli ale vârstnicului.Acest studiu și-a propus să evalueze corelația dintre nivelurile serice de vitamină D și rezistența la stres, declinul cognitiv și îmbătrânirea cu succes la vârstnicii din România.Un studiu clinic transversal a fost efectuat cu 89 de participanți având vârsta peste 55 de ani.Nivelurile serice de vitamină D au fost măsurate folosind analiza de chemiluminiscență, în timp ce funcția cognitivă a fost evaluată prin Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MOCA) și Geriatric Depression Scale.Stresul și reziliența au fost evaluate utilizând Scala de stres perceput și Testul de reziliență psihică Siebert.A fost identificată o corelație semnificativă între nivelurile scăzute de vitamina D și afectarea cognitivă, măsurată de MMSE și MOCA.Cu toate acestea, nu a fost găsită nicio relație semnificativă între nivelurile de vitamina D și scorurile de stres sau rezistență.Acest studiu sugerează că vitamina D joacă un rol în prevenirea declinului cognitiv la vârstnici, dar impactul său asupra stresului și rezilienței psihice necesită investigații suplimentare.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.011

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.360
Teacher spread0.345 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2024
Admission routes1
Has abstractyes

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