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Record W4408215717 · doi:10.1101/2025.03.04.25323064

Causal Bayesian networks to quantify the interactions that influence implementation success

2025· preprint· en· W4408215717 on OpenAlexaff
Steven Mascaro, Robyn Aitken, Melanie Barwick, Anne B. Chang, Pamela Laird, Gloria Lau, Gabrielle B. McCallum, Peter S Morris, Richard Norman, Maree Toombs, Roz Walker, André Schultz

Bibliographic record

VenuemedRxiv · 2025
Typepreprint
Languageen
FieldHealth Professions
TopicHealth Policy Implementation Science
Canadian institutionsHospital for Sick ChildrenUniversity of Toronto
Fundersnot available
KeywordsBayesian networkBayesian probabilityComputer scienceEconometricsArtificial intelligenceData scienceMathematics

Abstract

fetched live from OpenAlex

Abstract Despite the potential of evidence-based medical innovations to improve patient outcomes, their integration remains difficult. Implementation science aims to assist by identifying and deploying effective implementation strategies within complex health care settings. Determinant frameworks, such as the Consolidated Framework for Implementation Research (CFIR), help identify factors influencing implementation success but do not specify mechanisms or methods for selecting optimal strategies. Selection methods are largely empirical, highlighting the need for objective, quantifiable approaches. We developed causal Bayesian networks (BNs) to model the interdependencies amongst contextual factors, determinants and outcomes with a specific example: the detection and management of chonic wet cough in Indigenous Australian children in primary health care settings. The BNs, informed by CFIR domains and prior qualitative research, quantifies the impact of barriers and enablers on implementation outcomes. The BNs enable predictions of intervention effects, and the assessment and quantification of potential implementation strategies, or a combination of strategies. The BNs are linked to a simple survey that allows implementation strategies to be tailored for each setting and that was administered at several sites across Australia to validate the models. The overall process, including the BNs and surveys, constitutes a generalisable structured workflow for selecting the most promising strategies. We describe the model development and validation, and the broader applicability of our BN-based workflow in implementation science.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.031
metaresearch head score (Gemma)0.152
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.031
Threshold uncertainty score0.162

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0310.152
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0060.004
Science and technology studies0.0010.002
Scholarly communication0.0030.004
Open science0.0020.003
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0140.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.383
GPT teacher head0.657
Teacher spread0.274 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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