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Record W4408229495 · doi:10.1021/jacsau.5c00077

Data-Driven Search Algorithm for Discovery of Synthesizable Zeolitic Imidazolate Frameworks

2025· article· en· W4408229495 on OpenAlex
Soochan Lee, Hyein Jeong, Sungyeop Jung, Yeong-Jin Kim, Eunchan Cho, Joohan Nam, D. ChangMo Yang, Dong Yun Shin, Jung-Hoon Lee, Hyunchul Oh, Wonyoung Choe

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueJACS Au · 2025
Typearticle
Languageen
FieldChemistry
TopicZeolite Catalysis and Synthesis
Canadian institutionsArtificial Intelligence in Medicine (Canada)
FundersNational Research Foundation of KoreaKorea Institute of Science and Technology InformationKorea Institute of Science and TechnologyKorea UniversityUlsan National Institute of Science and Technology
KeywordsZeolitic imidazolate frameworkImidazolateComputer scienceParallel computingAlgorithmChemistryMetal-organic frameworkOrganic chemistry

Abstract

fetched live from OpenAlex

High Resolution Image Download MS PowerPoint Slide Zeolitic imidazolate frameworks (ZIFs), metal–organic analogues of zeolites, hold great potential for carbon-neutral applications due to their exceptional stability and porosity. However, ZIF discovery has been hindered by the limited topologies resulting from a mismatch between numerous predicted and few synthesized zeolitic networks. To address this, we propose a data-driven search algorithm using structural descriptors of known materials as a screening tool. From over 4 million zeolite structures, we identified potential ZIF candidates based on O–T–O angle differences, vertex symbols, and T–O–T angles. Energy calculations facilitated the ranking of ZIFs by their synthesizability, leading to the successful synthesis of three ZIFs with two novel topologies: UZIF-31 ( uft 1) and UZIF-32, -33 ( uft 2). Notably, UZIF-33 exhibited remarkable CO 2 selective adsorption. This study highlights the synergistic potential of combining structural predictions with chemical intuition to advance material discovery.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.820
Threshold uncertainty score0.658

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.298
Teacher spread0.271 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it