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Record W4408229662 · doi:10.1101/2025.02.28.640833

Managing populations after a disease outbreak: exploration of epidemiological consequences of managed host reintroduction following disease-driven host decline

2025· preprint· en· W4408229662 on OpenAlexaff
Jorge Arroyo‐Esquivel, Alyssa‐Lois M. Gehman, Fabio Sánchez

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2025
Typepreprint
Languageen
FieldMedicine
TopicZoonotic diseases and public health
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsHost (biology)OutbreakDiseaseEpidemiologyBiologyMedicineVirologyEcologyPathology

Abstract

fetched live from OpenAlex

Abstract Disease outbreaks in wild populations around the globe can lead to widespread mortality within populations, where recovery of individuals can be rare. An example of this population is the sunflower sea star Pyc-nopodia helianthioides in the Northeastern Pacific coast. The populations of this species, as well as many other sea star populations, have experienced massive mortality events due to an unidentified disease called Sea Star Wasting Disease (SSWD). Pycnopodia play a key role in providing top-down control of kelp grazers in rocky reefs across the Northeastern Pacific coast. This, combined with the massive declines in kelp coverage observed during the 2015-2016 marine heat wave observed in the Northeastern Pacific, has sparked an interest in reintroducing Pycnopodia individuals in the coast to potentially assist in recovery of the populations. However, the epidemiological implications of reintroducing healthy sea stars into the wild populations is an under-explored question. This work explores this question using a dynamical population model of Pycnopodia . We use this model to estimate the impacts of reintroducing healthy individuals into a wild sea star population. This analysis will provide valuable information for managers interested in restoring Pycnopodia populations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.014
Threshold uncertainty score0.028

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.044
GPT teacher head0.304
Teacher spread0.260 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venuebioRxiv (Cold Spring Harbor Laboratory)→Same topicZoonotic diseases and public health→French-language works237,207→