MétaCan
Menu
← Back to cohort
Record W4408293620 · doi:10.1101/2025.03.05.641582

Automatic detection of nociceptive pain levels using frequency bands from electroencephalographic (EEG) signals

2025· preprint· en· W4408293620 on OpenAlexaffabout
Rogelio Sotero Reyes-Galaviz, Luis Villaseñor-Pineda, Camilo E. Valderrama

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2025
Typepreprint
Languageen
FieldNeuroscience
TopicEEG and Brain-Computer Interfaces
Canadian institutionsUniversity of Winnipeg
Fundersnot available
KeywordsElectroencephalographyNociceptionAudiologyNeurosciencePsychologyMedicineInternal medicine

Abstract

fetched live from OpenAlex

Abstract Pain is considered an unpleasant but vital experience for every living being, it is extremely complex and subjective because it is composed of different variables related to their experiences. Their history, biological sex, socio/cultural context, mood, and hormonal changes can affect their perception. Nociceptive pain is more linked to tissue damage or stimulus, and this will always have a reaction that goes from its activation in the nociceptors in the peripheral nerves of the living being to the central nervous system. The most common way to assess pain today is to apply numerical scales or ”How much pain do you feel?” questionnaires, which are usually falsifiable and unreliable. Therefore, this work seeks to make use of biosignals such as Electroencephalography (EEG) to identify and evaluate pain at different levels. This nociceptive pain is generated by applying a laser on the back of the hand, which consists of three different intensities. It has been possible to differentiate between two levels of pain (high pain and low pain) with 83% accuracy using information from the power of frequency bands of the brain signal. Indicating that there are differences in the powers of the frequency bands as pain increases. Author summary Rogelio Sotero Reyes-Galaviz: Mechatronic engineer from the Polytechnic University of Tlaxcala (UPTlax), with a Master of Science degree in Biomedical Science and Technology at the Instituto Nacional de Astrofísica, Óptica y Electrónica (INAOE). He is currently pursuing a PhD in Biomedical Sciences and Technologies at INAOE. His research is focused on pain quantification using electrical brain signals (EEG) and machine learning methods. His lines of interest are Signal Processing, Electroencephalography, Stress, Music Therapy and Pain. ( rogeliosrg@inaoep.mx ) Luis Villaseñor-Pineda: Luis Villaseñor received his PhD degree in Computational Sciences from l’Université Joseph Fourier (now Université Grenoble-Alpes), France, in 1999. He is currently a senior researcher in the Computational Sciences department at the Instituto Nacional de Astrofísica, Óptica y Electŕonica, México, and a member of the Mexican Academy of Sciences, the Mexican Association of Natural Language Processing, and the Mexican System of Researchers (Level II). His research interests focus on human-computer communication using human language as well as different biosignals (speech, brain-signal, etc.). ( villasen@inaoep.mx ) Camilo E. Valderrama: Assistant Professor in the Applied Computer Science department at the University of Winnipeg, specializing in the application of machine learning, statistical models, and signal processing to extract meaningful patterns and support decision-making processes. His research spans diverse areas, including affordable fetal monitoring, reducing redundant laboratory tests in intensive care units, protecting children from unhealthy-food advertising, and validating neuromarketing principles. Prior to this, he completed a two-year postdoctoral fellowship at the University of Calgary. He holds a Ph.D. in Computer Science with a concentration in Biomedical Informatics from Emory University (Atlanta, GA, USA), a Master of Science in Informatics, and a Bachelor of Science in Software Systems Engineering from Universidad Icesi (Cali, Colombia). ( c.valderrama@uwinnipeg.ca )

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0020.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.250
Teacher spread0.223 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

Explore more

Same venuebioRxiv (Cold Spring Harbor Laboratory)→Same topicEEG and Brain-Computer Interfaces→French-language works237,207→