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Record W4408295663 · doi:10.3390/curroncol32030155

Barriers and Facilitators to Delivering Multifactorial Risk Assessment and Communication for Personalized Breast Cancer Screening: A Qualitative Study Exploring Implementation in Canada

2025· article· en· W4408295663 on OpenAlexafffundvenueabout
Meghan J. Walker, Antonis C. Antoniou, Mireille J. M. Broeders, Jennifer D. Brooks, Tim Carver, Jocelyne Chiquette, Douglas F. Easton, Andrea Eisen, Laurence Eloy, D. Gareth Evans, Samantha Fienberg, Yann Joly, Raymond H. Kim, Bartha Maria Knoppers, Aïsha Lofters, Hermann Nabi, Nora Pashayan, Tracy Stockley, Michel Dorval, Jacques Simard, Anna M. Chiarelli

Bibliographic record

VenueCurrent Oncology · 2025
Typearticle
Languageen
FieldMedicine
TopicGlobal Cancer Incidence and Screening
Canadian institutionsPrincess Margaret Cancer CentreMcGill UniversityUniversité LavalMinistère de la Santé et des Services Sociaux (Québec)Sunnybrook Health Science CentreWomen's College HospitalCancer Care OntarioPublic Health OntarioUniversity Health NetworkUniversity of Toronto
FundersCanadian Institutes of Health ResearchCancer Research UKGenome Canada
KeywordsMedicineRisk assessmentThematic analysisFocus groupBreast cancerQualitative researchRisk management toolsScale (ratio)PopulationFamily medicineEnvironmental healthCancerInternal medicineComputer science

Abstract

fetched live from OpenAlex

Many jurisdictions are considering a shift to risk-stratified breast cancer screening; however, evidence on the feasibility of implementing it on a population scale is needed. We conducted a prospective cohort study in the PERSPECTIVE I&I project to produce evidence on risk-stratified breast screening and recruited 3753 participants to undergo multifactorial risk assessment from 2019-2021. This qualitative study explored the perspectives of study personnel on barriers and facilitators to delivering multifactorial risk assessment and risk communication. One focus group and three one-on-one interviews were conducted and a thematic analysis conducted which identified five themes: (1) barriers and facilitators to recruitment for multifactorial risk assessment, (2) barriers and facilitators to completion of the risk factor questionnaire, (3) additional resources required to implement multifactorial risk assessment, (4) the need for a person-centered approach, and (5) and risk literacy. While risk assessment and communication processes were successful overall, key barriers were identified including challenges with collecting comprehensive breast cancer risk factor information and limited resources to execute data collection and risk communication activities on a large scale. Risk assessment and communication processes will need to be optimized for large-scale implementation to ensure they are efficient but robust and person-centered.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.020
metaresearch head score (Gemma)0.033
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: Qualitative
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.279
Threshold uncertainty score0.561

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0200.033
Meta-epidemiology (narrow)0.0000.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.002
Science and technology studies0.0140.007
Scholarly communication0.0040.002
Open science0.0020.005
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.257
GPT teacher head0.547
Teacher spread0.290 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2025
Admission routes4
Has abstractyes

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