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Record W4408308024 · doi:10.1016/j.cep.2025.110275

Scaling process intensification technologies: what does it take to deploy?

2025· article· en· W4408308024 on OpenAlexaff
Daria C. Boffito

Bibliographic record

VenueChemical Engineering and Processing - Process Intensification · 2025
Typearticle
Languageen
FieldEngineering
TopicInnovative Microfluidic and Catalytic Techniques Innovation
Canadian institutionsPolytechnique Montréal
FundersUniversity of Twente
KeywordsScalingProcess (computing)Computer scienceProcess managementBusinessMathematicsOperating system

Abstract

fetched live from OpenAlex

• Key enablers for scaling up process-intensification (PI) technologies are identified • PI technologies rely less on the electricity grid vs. traditional ones • Interdisciplinary collaborations and lab-to-market partnerships are crucial • Business development experts should be involved at early TRL (3, 4) • Techno-economic analysis and LCA de-risk business development at TRL 3, 4 Process intensification (PI) has emerged as a transformative approach to enhancing efficiency, sustainability, and economics across chemical and manufacturing industries. However, within its dedicated communities, there is recognition of a persistent gap in transitioning these innovations from laboratory-scale success to widespread industrial adoption. Scaling up PI technologies is far more complex than simply replicating laboratory conditions on a larger scale. Challenges such as the integration with existing units and processes, proving economic viability, and navigating regulatory requirements often impede the practical implementation of PI innovations. This paper aims to identify the key enablers for scaling up PI technologies by presenting a roadmap to bridge the gap between concept and commercialization. While robust engineering design frameworks and advanced modeling tools are crucial, interdisciplinary collaborations and lab-to-market partnerships (or integrated scaling collaborations) are equally critical to drive the successful adoption of PI at the industrial scale.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.020
metaresearch head score (Gemma)0.030
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.020
Threshold uncertainty score0.107

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0200.030
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0030.002
Science and technology studies0.0020.005
Scholarly communication0.0140.022
Open science0.0050.004
Research integrity0.0100.007
Insufficient payload (model declined to judge)0.0130.008

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.260
Teacher spread0.250 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations10
Published2025
Admission routes1
Has abstractyes

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Same venueChemical Engineering and Processing - Process IntensificationSame topicInnovative Microfluidic and Catalytic Techniques InnovationFrench-language works237,207