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Record W4408308024 · doi:10.1016/j.cep.2025.110275

Scaling process intensification technologies: what does it take to deploy?

2025· article· en· W4408308024 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueChemical Engineering and Processing - Process Intensification · 2025
Typearticle
Languageen
FieldEngineering
TopicInnovative Microfluidic and Catalytic Techniques Innovation
Canadian institutionsPolytechnique Montréal
FundersUniversity of Twente
KeywordsScalingProcess (computing)Computer scienceProcess managementBusinessMathematicsOperating system

Abstract

fetched live from OpenAlex

• Key enablers for scaling up process-intensification (PI) technologies are identified • PI technologies rely less on the electricity grid vs. traditional ones • Interdisciplinary collaborations and lab-to-market partnerships are crucial • Business development experts should be involved at early TRL (3, 4) • Techno-economic analysis and LCA de-risk business development at TRL 3, 4 Process intensification (PI) has emerged as a transformative approach to enhancing efficiency, sustainability, and economics across chemical and manufacturing industries. However, within its dedicated communities, there is recognition of a persistent gap in transitioning these innovations from laboratory-scale success to widespread industrial adoption. Scaling up PI technologies is far more complex than simply replicating laboratory conditions on a larger scale. Challenges such as the integration with existing units and processes, proving economic viability, and navigating regulatory requirements often impede the practical implementation of PI innovations. This paper aims to identify the key enablers for scaling up PI technologies by presenting a roadmap to bridge the gap between concept and commercialization. While robust engineering design frameworks and advanced modeling tools are crucial, interdisciplinary collaborations and lab-to-market partnerships (or integrated scaling collaborations) are equally critical to drive the successful adoption of PI at the industrial scale.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.748
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.002
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.260
Teacher spread0.250 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it