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Record W4408318781 · doi:10.1002/mrm.30468

Automated fibrosis segmentation from wideband post‐contrast T1∗$$ {T}_1^{\ast } $$ mapping in an animal model of ischemic heart disease with implantable cardioverter‐defibrillators

2025· article· en· W4408318781 on OpenAlexafffund
Calder Sheagren, Terenz Escartin, Jaykumar Patel, Jennifer Barry, Graham A. Wright

Bibliographic record

VenueMagnetic Resonance in Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicCardiac Imaging and Diagnostics
Canadian institutionsUniversity of TorontoSunnybrook Health Science Centre
FundersCanadian Institutes of Health Research
KeywordsThresholdingSegmentationArtifact (error)Artificial intelligenceMedicinePattern recognition (psychology)Contrast (vision)Computer scienceImage (mathematics)

Abstract

fetched live from OpenAlex

PURPOSE: maps with an ICD present and compare it to manually tuned thresholding of synthetic LGE images with an ICD present and standard LGE without an ICD present. METHODS: Seven swine received an ischemia-reperfusion myocardial infarction and were imaged at 3 T 4-5 weeks post-infarct with and without an ICD. Mapping-based thresholding was performed using synthetic LGE and artifact-corrected cluster-thresholding methods, both employing connected component filtering. Standard pixel signal intensity thresholding was performed on the conventional LGE without an ICD. Volumetric accuracy is relative to conventional LGE and Dice similarity between SynLGE and cluster-based segmentations were evaluated. RESULTS: No statistical significance was observed between LGE volumes without an ICD and both SynLGE and artifact-corrected cluster-threshold volumes with an ICD, when using connected component filtering. Additionally, Dice alignment between SynLGE and cluster-thresholding was high for healthy myocardium (0.96), dense scar (0.83), and dense scar union gray zone (0.91) when artifact correction and connected component filtering were implemented. CONCLUSION: maps holds promise for a reproducible approach to scar segmentation in the presence of ICDs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.261
Teacher spread0.252 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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