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Record W4408327140 · doi:10.1371/journal.pone.0319576

Psychological stress associated with prognostic uncertainties in recently diagnosed Parkinson’s disease patients: A qualitative study

2025· article· en· W4408327140 on OpenAlexaffabout
Yasmin H. Aboelzahab, Azadeh Bojmehrani, Y Ahmed, Heather Boon, Connie Marras, Richard Foty

Bibliographic record

VenuePLoS ONE · 2025
Typearticle
Languageen
FieldMedicine
TopicParkinson's Disease Mechanisms and Treatments
Canadian institutionsToronto Western HospitalUniversity Health NetworkUniversity of Toronto
Fundersnot available
KeywordsIntrapersonal communicationSocial supportMedicineQuality of life (healthcare)DiseaseMental healthQualitative researchClinical psychologyHealth careParkinson's diseasePsychiatryPatient experiencePsychologyInterpersonal communicationInternal medicineNursingPsychotherapist

Abstract

fetched live from OpenAlex

BACKGROUND: Parkinson's disease (PD) is a common neurodegenerative disorder that negatively impacts thousands of patients in Canada. The unexpected nature of PD is associated with a decline in mental health. The highest level of psychological stress occurs during the early years following the diagnosis. OBJECTIVES: To understand the psychological stress associated with prognostic uncertainties in recently diagnosed PD patients, uncover the gaps in the current support systems, and recommend areas for improvement in the support services that aim to decrease the psychological stress associated with receiving the PD diagnosis. METHODS: An exploratory qualitative study was conducted using semi-structured interviews with 13 PD patients diagnosed for more than 6 months and less than 5 years. Participants were recruited from the Toronto Western Hospital Movement Disorders Clinic, Toronto, Ontario, Canada until saturation of key themes was reached. RESULTS: Five major themes were identified capturing the lived experiences of PD patients following diagnosis: 1) the circumstances of receiving the diagnosis and its psychological impact on PD patients, 2) the impact of intrapersonal factors on the PD journey, 3) the role of social relationships in PD patient's life, 4) the interaction of PD patients with different elements of the healthcare system, and 5) support services available for recently diagnosed PD patients. CONCLUSIONS: This study uncovers the psychological burden faced by PD patients due to prognostic uncertainties and insufficient support systems. It emphasizes the importance of a patient-centered approach for improving their quality of life and healthcare experiences through personalized support services.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.008
metaresearch head score (Gemma)0.013
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: Qualitative
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.018
Threshold uncertainty score0.047

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0080.013
Meta-epidemiology (narrow)0.0000.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0070.006
Scholarly communication0.0030.003
Open science0.0010.005
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.051
GPT teacher head0.325
Teacher spread0.274 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes2
Has abstractyes

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