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ARIG-GCN: Anatomical Relationship and Isomorphic Graph Approximation Guided Graph Convolutional Network for Automated ASPECTS Scoring on Non-Contrast CT

2025· article· en· W4408356212 on OpenAlexaboutno aff
Ning Li, Zhe Qu, Jie Wang, Hulin Kuang

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicRadiomics and Machine Learning in Medical Imaging
Canadian institutionsnot available
FundersResearch and DevelopmentNational Natural Science Foundation of China
KeywordsComputer scienceGraphContrast (vision)Artificial intelligenceTheoretical computer science

Abstract

fetched live from OpenAlex

The Alberta Stroke Program Early CT Score (AS-PECTS) is a systematic method for assessing the extent of early ischemic changes on non-contrast CT (NCCT) of patients with acute ischemic stroke (AIS). The ASPECTS regions are anatomically and physiologically interconnected, making them suitable for analysis by graph neural networks. However, most existing methods fail to effectively use the relationships and bilateral differences. This study designs an Anatomical Relationship and Isomorphic Graph approximation guided Graph Convolutional Network for ASPECTS scoring on NCCT. Firstly, we propose a node construction guided by anatomical structures, i.e., utilizing the region anatomical relationship adjacency matrix of the ASPECTS regions to build the nodes. Secondly, to optimize the information propagation among nodes, we propose isomorphic graph approximation, utilizing edge learning, connectivity-based subgraph selection, and supervised isomorphic subgraph approximation to supervise the construction of isomorphic subgraphs. We validate our method on private AIS datasets which included NCCT scans of 257 AIS patients. The results show that the proposed method achieves interclass correlation coefficients of 0.8554 for total ASPECTS, and accuracy of 90.61% for dichotomized ASPECTS scoring (4), outperforming 9 state-of-the-art methods.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.018
Threshold uncertainty score0.036

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.302
Teacher spread0.285 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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