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Record W4408519581 · doi:10.1109/trpms.2025.3551946

Generative Inpainting-Based Anomaly Detection for CT Liver Tumor Detection

2025· article· en· W4408519581 on OpenAlexaff
Yongyi Shi, Chuang Niu, Amber L. Simpson, Bruno De Man, Richard Kinh Gian, Ge Wang

Bibliographic record

VenueIEEE Transactions on Radiation and Plasma Medical Sciences · 2025
Typearticle
Languageen
FieldComputer Science
TopicAnomaly Detection Techniques and Applications
Canadian institutionsQueen's University
FundersNational Institute of Biomedical Imaging and BioengineeringNational Cancer Institute
KeywordsInpaintingAnomaly detectionArtificial intelligenceAnomaly (physics)Pattern recognition (psychology)Generative grammarComputer scienceComputer visionImage (mathematics)Physics

Abstract

fetched live from OpenAlex

CT is a main modality for imaging liver diseases, valuable in detecting and localizing liver tumors. Traditional anomaly detection methods analyze reconstructed images to identify pathological structures. However, these methods may produce suboptimal results, overlooking subtle differences among various tissue types. To address this challenge, here we employ generative diffusion prior to inpaint the liver as the reference facilitating anomaly detection. Specifically, we use an adaptive threshold to extract a mask of abnormal regions, which are then inpainted using a diffusion prior to calculating an anomaly score based on the discrepancy between the original CT image and the inpainted counterpart. Our methodology has been tested on two liver CT datasets, demonstrating a significant improvement in detection accuracy, with a 7.9% boost in the area under the curve (AUC) compared to the state-of-the-art. This performance gain underscores the potential of our approach to refine the radiological assessment of liver diseases.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.991
Threshold uncertainty score0.897

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.266
Teacher spread0.251 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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