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Record W4408676077 · doi:10.3389/fpubh.2025.1502006

Global randomized controlled trial of knowledge translation of children’s environmental health

2025· article· en· W4408676077 on OpenAlexaffabout
Rivka Green, Christine Till, Jana El-Sabbagh, Allya DaCosta, Erica Phipps, Carly Goodman, David B. Flora, Bruce P. Lanphear

Bibliographic record

VenueFrontiers in Public Health · 2025
Typearticle
Languageen
FieldEnvironmental Science
TopicEffects and risks of endocrine disrupting chemicals
Canadian institutionsSimon Fraser UniversityYork UniversityHospital for Sick Children
Fundersnot available
KeywordsHarmEnvironmental healthMedicineRandomized controlled trialPsychologySocial psychologyPathology

Abstract

fetched live from OpenAlex

Objectives Toxic chemicals can harm children’s brain development, but the public’s understanding of these harmful impacts is largely unknown. People’s knowledge of toxic chemicals and their awareness of how to reduce children’s exposure was examined. This study also assessed whether a video was efficacious in increasing knowledge about toxic chemicals and brain development and encouraging behavioral change to reduce exposure to toxic chemicals. Methods 15,594 participants of child-bearing age (18–45 years old) from five countries (Canada, United States, United Kingdom, India, and Australia) were surveyed via CloudResearch’s Prime Panels®. After completing a baseline survey, Prevention of Toxic Chemicals in the Environment for Children Tool (PRoTECT), participants were randomly assigned to watch a knowledge translation video (experimental group) or serve as a control group. Next, participants were asked about barriers and intentions to reduce exposure to toxic chemicals. After 6 weeks, a subset (n = 4,842) of participants were surveyed with PRoTECT and asked whether they modified behaviors to reduce exposure to toxic chemicals or plan to speak to their healthcare provider (HCP) about toxic chemicals. Results Participants expressed strong preferences for lowering exposures and preventing disabilities. Participants who knew more about the impact of toxic chemicals on children’s health were more likely to prefer investing in prevention and reducing their exposures. Participants who viewed the video showed significantly greater changes in PRoTECT scores. At the 6-week follow-up, no differences in behavioral changes were observed by group assignment, but two-thirds of all participants reported making changes to reduce their exposures and half intended to speak with their HCP. Conclusion There were significant differences in knowledge and preferences by group assignment, but systemic barriers, such as cost of non-toxic products and difficulty determining how and where to buy them, hindered people from making changes to reduce their exposures to toxic chemicals.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.008
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.028
Threshold uncertainty score0.092

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.008
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0040.003
Bibliometrics0.0010.001
Science and technology studies0.0010.002
Scholarly communication0.0010.002
Open science0.0010.001
Research integrity0.0030.004
Insufficient payload (model declined to judge)0.0280.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.331
Teacher spread0.320 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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