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Record W4408690838 · doi:10.1117/12.3040648

Predicting outcomes of kidney transplantation using quantitative ultrasound and photoacoustics (Conference Presentation)

2025· article· en· W4408690838 on OpenAlexaff
Sarah J. Dykstra, Jihye Baek, Alexander Koven, Xiaolin He, Michael C. Kolios, Kevin J. Parker, Darren A. Yuen, Eno Hysi

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicOrgan Transplantation Techniques and Outcomes
Canadian institutionsSt. Michael's Hospital
Fundersnot available
KeywordsPresentation (obstetrics)TransplantationUltrasoundComputer scienceKidney transplantationMedicineRadiologyInternal medicine

Abstract

fetched live from OpenAlex

Kidney transplantation is the best treatment for renal failure, but demand outstrips supply, leading to long waits. Current methods can’t assess donor kidney quality non-invasively assessment. We developed quantitative ultrasound (qUS) and photoacoustic (qPA) imaging techniques to address this. Our H-scan (qUS) maps fibrotic burden, while multiwavelength qPA examines ischemic reperfusion injury (IRI) during transplant surgery. A trial at St. Michael’s Hospital involved 70 patients. H-scan correlated well with biopsy results and predicted long-term kidney function better. qPA imaging revealed significant differences in perfusion and oxygenation between living and deceased donors, indicating that our methods can improve transplant outcomes through real-time surgical interventions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.006
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.342
Teacher spread0.311 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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