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Record W4408733262 · doi:10.1016/j.focus.2025.100334

Spatially Continuous Maps of Disease Risk: An Analysis of Mortality Disparities in the United States

2025· article· en· W4408733262 on OpenAlexafffund
Sofia Ruiz-Suarez

Bibliographic record

VenueAJPM Focus · 2025
Typearticle
Languageen
FieldMedicine
TopicData-Driven Disease Surveillance
Canadian institutionsUniversity of TorontoCentre for Global Health ResearchSt. Michael's Hospital
FundersNatural Sciences and Engineering Research Council of CanadaUniversity of Toronto
KeywordsMedicineDiseaseGeographyEnvironmental healthInternal medicine

Abstract

fetched live from OpenAlex

Introduction: In the U.S., race and education have proven to be critical determinants of health outcomes inequalities, influenced by both location and time. Lung cancer (primarily linked to smoking), along with drug overdoses, alcohol poisoning, and suicide, emerge as important contributors to mortality risk. The purpose of this study is to enhance the understanding of geographic disparities in mortality related to lung cancer and external causes of death in the U.S. This study focuses on a finer geographic scale while examining the components of variation in mortality rates, stratifying by both education and race. Methods: This study used an aggregated spatial model and Bayesian inference to create continuous maps of risk. The study analyzes mortality counts from 1999 to 2015. This approach not only allows one to analyze and combine data sources at different spatial resolutions in a shorter time, but also facilitates standardized comparisons across age, sex, education, and spatial location. Results: Education emerged as the primary source of variation in both types of mortality, with growing disparities since 1999. Spatially, mortality risk varies more among the less educated and less among the more educated. Lung cancer rates have declined for the most educated but stayed steady for the less educated, while external causes of death rates rose for the less educated but remain unchanged for the more educated ones. Racial differences are significant for external causes of death but minimal for lung cancer. Conclusions: These findings highlight the need to go beyond education as a simple predictor variable in mortality studies, while also accounting for the differences in the nature of spatial variation. While the impact of education on mortality rates is unsurprising, the fact that Black Americans on average encounter inferior socioeconomic conditions compared to White Americans, may explain why this group is usually recognized at higher risk. This investigation suggests that addressing racial disparities in education levels could help to reduce tobacco-related mortality discrepancies effectively.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.018
Threshold uncertainty score0.977

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.299
Teacher spread0.286 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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