MétaCan
Menu
Back to cohort
Record W4408768557 · doi:10.3389/fopht.2025.1545602

Risk factors of retinal vein occlusion in East Asia: a meta-analysis

2025· review· en· W4408768557 on OpenAlexaboutno aff
Ziman Jiao, Yuxin Liu, Haiyu Li, Xin Chen, Guanghui Liu

Bibliographic record

VenueFrontiers in Ophthalmology · 2025
Typereview
Languageen
FieldMedicine
TopicRetinal Diseases and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineCochrane LibraryOdds ratioRetinal VeinInternal medicineDiabetes mellitusConfidence intervalHomocysteineOcclusionHyperlipidemiaMeta-analysisEndocrinology

Abstract

fetched live from OpenAlex

Objective With the intention of developing a more targeted control strategy for retinal vein occlusion (RVO) in East Asian populations, a meta-analysis was conducted to evaluate the risk factors associated with RVO in this region. Methods PubMed, Web of Science, Cochrane Library, CNKI, Wanfang and VIP databases were searched for studies that reported risk factors of RVO in East Asia, published from the establishment of the database to May 2024. To further filter the articles, Newcastle-Ottawa Scale (NOS) evaluation method was utilized to assess the quality of selected articles. After valid data were extracted, Meta-analysis was performed by Review Manager software. Results A total of 21 literatures were included, including 27561 cases in the RVO group (Case group) and 514578 cases in the non-retinal vein occlusion (NRVO) group (Control group). Results of meta-analysis showed that chronic kidney disease [odds ratio (OR)=4.14, 95% confidence interval (CI): (1.86%, 9.24%)], hypertension [OR=4.11, 95% CI: (3.09%, 5.48%)], hyperlipidemia [OR=3.45, 95%CI: (2.32%, 5.12%)], diabetes mellitus [OR=3.00, 95%CI: (1.88%, 4.80%)], homocysteine [OR=0.87, 95%CI: (0.59%, 1.15%)], have statistically significant differences between the RVO group and the NRVO group(P<0.05). Conclusion The occurrence of RVO is closely related to its risk factors, such as chronic kidney disease, hypertension, hyperlipidemia, diabetes mellitus and high homocysteine. In the process of diagnosis and treatment of RVO, doctors should focus on the above risk factors to prevent the occurrence of the disease.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.011
metaresearch head score (Gemma)0.017
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: Meta-analysis
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.014
Threshold uncertainty score0.056

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0110.017
Meta-epidemiology (narrow)0.0030.001
Meta-epidemiology (broad)0.0140.046
Bibliometrics0.0050.006
Science and technology studies0.0010.000
Scholarly communication0.0030.001
Open science0.0020.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.067
GPT teacher head0.375
Teacher spread0.308 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations5
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueFrontiers in OphthalmologySame topicRetinal Diseases and TreatmentsFrench-language works237,207