Comparative Clinical and Laboratory Assessment of the Effectiveness of Rehabilitation Therapy in Patients with Osteoarthritis of the Knee Joints
Bibliographic record
Abstract
Purpose. To evaluate the effectiveness of the course administration of an ozone-oxygen mixture into the periarticular tissues of the knee joint in patients with osteoarthritis who underwent total arthroplasty of one of the joints and to study the effect of this technique on the state of lipid peroxidation and the antioxidant defense system of the body relative to traditional methods of restorative treatment. Materials and methods . The study included 120 patients with bilateral gonarthrosis after endoprosthetics of one of the knee joints. The average age of the patients was 60 [46; 76] years. Depending on the method of rehabilitation treatment, the patients were divided into 3 equal groups (n=40): the 1st group was prescribed periarticular subcutaneous ozone therapy in combination with therapeutic exercise, the 2nd group — magnetotherapy and electrophoresis on the knee joint area in combination with therapeutic exercise, and 3rd group — only the complex of therapeutic exercise. In all patients, before and after rehabilitation treatment (after 14 days and 3 months), the clinico-functional status was assessed using the Western Ontario and McMaster Universities Osteoarthritis Index scale and the indicators of the intensity of the free radical oxidation processes and the activity of antioxidant protection were studied. Results. A detailed analysis of the clinico-functional state among patients of group 1 relative to group 2 and 3 revealed the best “long-term” result: a marked decrease in pain (p <0.05, p <0.0001), stiffness (p <0.05, p <0.0001), limitations physical activity (p <0.01, p <0.0001) due to the improvement of the main indicators of the antioxidant protection system against the background of ongoing therapy: catalase (p <0.01) and superoxide dismutase (p <0.01). Conclusion . The use of periarticular ozone therapy makes it possible to achieve a more stable positive effect in patients after total knee arthroplasty relative to traditional methods of restorative treatment due to its pronounced antioxidant effect aimed at stabilizing the processes of lipid peroxidation.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.003 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".