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Record W4408849024 · doi:10.7759/cureus.81231

Glioblastoma Masquerading as Metastasis in a Routine Follow-Up of a 79-Year-Old Woman

2025· article· en· W4408849024 on OpenAlexaff
Rana Moshref, Abdurrahim Elashaal

Bibliographic record

VenueCureus · 2025
Typearticle
Languageen
FieldMedicine
TopicGlioma Diagnosis and Treatment
Canadian institutionsWindsor Regional HospitalLondon Health Sciences Centre
Fundersnot available
KeywordsMedicineGlioblastomaMetastasisGeneral surgeryPathologyRadiologyInternal medicineCancerCancer research

Abstract

fetched live from OpenAlex

Glioblastoma is the most aggressive and common primary brain tumor. Diagnosis is based on imaging and is confirmed through a brain biopsy. Multimodal treatment, including gross total resection, radiotherapy, and chemotherapy, is typically required. We report a case of a 79-year-old woman, a former smoker, who presented with a headache and generalized weakness and was found to have multiple brain lesions. The patient was diagnosed with glioblastoma and underwent partial resection. Multiple glioblastomas are a rare presentation and can be multicentric or multifocal. Patients with this presentation typically exhibit symptoms of high intracranial pressure. Glioblastomas have a poor prognosis despite multidisciplinary management. Glioblastoma should be considered a differential diagnosis for patients with multiple brain lesions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.011

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0020.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.291
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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