Leucocytosis-induced artefactual hypoglycaemia in the setting of chronic neutrophilic leukaemia
Bibliographic record
Abstract
A man in his late 70s with newly diagnosed chronic neutrophilic leukaemia with marked leucocytosis was found to have recurrent low plasma glucose levels on routine bloodwork. Nevertheless, he did not exhibit any signs or symptoms of hypoglycaemia, and capillary blood glucose measurements taken at the same time were within normal limits. Time-dependent plasma glucose concentration decline with delayed processing confirmed the suspected diagnosis of artefactual hypoglycaemia secondary to hyperleucocytosis. This phenomenon is caused by excessive in vitro glycolysis, which can be mitigated by rapid sample processing or the use of tubes containing glycolysis inhibitors. This case report adds to the existing body of evidence on artefactual hypoglycaemia with the aim of raising awareness of this entity among healthcare professionals. In asymptomatic individuals with low glucose measurements, the possibility of spurious results should be considered prior to initiating further diagnostic work-up.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".